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10.1128/CMR.00124-13 http://scihub22266oqcxt.onion/10.1128/CMR.00124-13 C4135891!4135891!24982317     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Clin+Microbiol+Rev 2014 ; 27 (3): 463-81 Nephropedia Template TP {{tp|p=24982317|t=2014. Viruses and Human Cancers: a Long Road of Discovery of Molecular Paradigms |pdf=|usr=}}{{24982317}} gab.com Text Viruses and Human Cancers: a Long Road of Discovery of Molecular Paradigms JO: Clin Microbiol Rev http://www.kidney.de/pget.php?&tw=1&pmid=24982317 #FOAvip SUMMARY: About a fifth of all human cancers worldwide are caused by infectious agents. In 12% of cancers, seven different viruses have been causally linked to human oncogenesis: Epstein-Barr virus, hepatitis B virus, human papillomavirus, human T-cell lymphotropic virus, hepatitis C virus, Kaposi's sarcoma herpesvirus, and Merkel cell polyomavirus. Here, we review the many molecular mechanisms of oncogenesis that have been discovered over the decades of study of these viruses. We discuss how viruses can act at different stages in the complex multistep process of carcinogenesis. Early events include their involvement in mutagenic events associated with tumor initiation such as viral integration and insertional mutagenesis as well as viral promotion of DNA damage. Also involved in tumor progression is the dysregulation of cellular processes by viral proteins, and we describe how this has been investigated by studies in cell culture and in experimental animals and by molecular cellular approaches. Also important are the molecular mechanisms whereby viruses interact with the immune system and the immune evasion strategies that have evolved. Twit Text FOAVip Viruses and Human Cancers: a Long Road of Discovery of Molecular Paradigms ????Clin Microbiol Rev http://www.kidney.de/pget.php?&tw=1&pmid=24982317 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24982317 #FOAvip English Wikipedia <ref>{{Cite pmid|24982317}}</ref> Viruses and Human Cancers: a Long Road of Discovery of Molecular Paradigms #MMPMID24982317 White MK; Pagano JS; Khalili K Clin Microbiol Rev 2014[Jul]; 27 (3): 463-81 PMID24982317show ga SUMMARY: About a fifth of all human cancers worldwide are caused by infectious agents. In 12% of cancers, seven different viruses have been causally linked to human oncogenesis: Epstein-Barr virus, hepatitis B virus, human papillomavirus, human T-cell lymphotropic virus, hepatitis C virus, Kaposi's sarcoma herpesvirus, and Merkel cell polyomavirus. Here, we review the many molecular mechanisms of oncogenesis that have been discovered over the decades of study of these viruses. We discuss how viruses can act at different stages in the complex multistep process of carcinogenesis. Early events include their involvement in mutagenic events associated with tumor initiation such as viral integration and insertional mutagenesis as well as viral promotion of DNA damage. Also involved in tumor progression is the dysregulation of cellular processes by viral proteins, and we describe how this has been investigated by studies in cell culture and in experimental animals and by molecular cellular approaches. Also important are the molecular mechanisms whereby viruses interact with the immune system and the immune evasion strategies that have evolved. äViruses and Human Cancers: a Long Road of Discovery of Molecular Parad(epmc).pdf DeepDyve Pubget Overpricing