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Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Org+Biomol+Chem 2014 ; 12 (35): 6837-41 Nephropedia Template TP
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Highly Selective Fluorescence off-on Probes for Biothiols and Imaging in Live Cells #MMPMID25047799
Zhang D; Chen W; Kang J; Ye Y; Zhao Y; Xian M
Org Biomol Chem 2014[Sep]; 12 (35): 6837-41 PMID25047799show ga
Three sulfonyl benzothiazole-based fluorescent probes (RSHP1, RSHP2, and RSHP3) for the detection of biothiols (cysteine, homocysteine, and glutathione) are developed based on thiol-mediated nucleophilic aromatic substitutions. The probes exhibited good selectivity and sensitivity toward biothiols over other analytes. The probes were successfully applied for visualizing endogenous thiols in living cells.