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10.4161/cbt.29501 http://scihub22266oqcxt.onion/10.4161/cbt.29501 C4128859!4128859!24918434     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cancer+Biol+Ther 2014 ; 15 (9): 1163-73 Nephropedia Template TP {{tp|p=24918434|t=2014. Coronin3 regulates gastric cancer invasion and metastasis by interacting with Arp2 |pdf=|usr=}}{{24918434}} gab.com Text Coronin3 regulates gastric cancer invasion and metastasis by interacting with Arp2 JO: Cancer Biol Ther http://www.kidney.de/pget.php?&tw=1&pmid=24918434 #FOAvip Coronin3 expression is increased in gastric cancer (GC) tissues and can promote GC invasion and metastasis. However, the mechanisms underlying Coronin3 function in GC remain unclear. In this study, we aimed to explore the interacting molecules essential for the tumor-promoting effects of Coronin3 in GC. Using mass spectrometric analysis, functional studies, and immunohistochemistry, we found that Arp2 interacted with Coronin3, and ectopic expression of Arp2 promoted GC cell migration and invasion, while Arp2 knockdown suppressed whole-cell motility and attenuated the Coronin3-mediated upregulation of cell migration and invasion. In addition, both proteins correlated with the metastatic status of GC patients. Furthermore, survival analyses demonstrated that both Coronin3 and Arp2 correlated with overall GC patient survival, and the combination of Coronin3 and Arp2 most accurately predicted GC patient prognosis. Combined, these data demonstrate that Coronin3 can regulate GC invasion and metastasis through Arp2, and the combination of Coronin3 and Arp2 provides a potential marker for predicting GC prognosis. Twit Text FOAVip Coronin3 regulates gastric cancer invasion and metastasis by interacting with Arp2 ????Cancer Biol Ther http://www.kidney.de/pget.php?&tw=1&pmid=24918434 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24918434 #FOAvip English Wikipedia <ref>{{Cite pmid|24918434}}</ref> Coronin3 regulates gastric cancer invasion and metastasis by interacting with Arp2 #MMPMID24918434 Sun Y; Shang Y; Ren G; Zhou L; Feng B; Li K; Deng L; Liang J; Lu Y; Wang X Cancer Biol Ther 2014[Sep]; 15 (9): 1163-73 PMID24918434show ga Coronin3 expression is increased in gastric cancer (GC) tissues and can promote GC invasion and metastasis. However, the mechanisms underlying Coronin3 function in GC remain unclear. In this study, we aimed to explore the interacting molecules essential for the tumor-promoting effects of Coronin3 in GC. Using mass spectrometric analysis, functional studies, and immunohistochemistry, we found that Arp2 interacted with Coronin3, and ectopic expression of Arp2 promoted GC cell migration and invasion, while Arp2 knockdown suppressed whole-cell motility and attenuated the Coronin3-mediated upregulation of cell migration and invasion. In addition, both proteins correlated with the metastatic status of GC patients. Furthermore, survival analyses demonstrated that both Coronin3 and Arp2 correlated with overall GC patient survival, and the combination of Coronin3 and Arp2 most accurately predicted GC patient prognosis. Combined, these data demonstrate that Coronin3 can regulate GC invasion and metastasis through Arp2, and the combination of Coronin3 and Arp2 provides a potential marker for predicting GC prognosis. äCoronin3 regulates gastric cancer invasion and metastasis by interacti(epmc).pdf DeepDyve Pubget Overpricing