Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1016/j.mayocp.2014.02.014 http://scihub22266oqcxt.onion/10.1016/j.mayocp.2014.02.014 C4122123!4122123!24943699     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Mayo+Clin+Proc 2014 ; 89 (6): 850-8 Nephropedia Template TP {{tp|p=24943699|t=2014. Breakthroughs in Cell Therapy for Heart Disease: Focus on Cardiosphere-Derived Cells |pdf=|usr=}}{{24943699}} gab.com Text Breakthroughs in Cell Therapy for Heart Disease: Focus on Cardiosphere-Derived Cells JO: Mayo Clin Proc http://www.kidney.de/pget.php?&tw=1&pmid=24943699 #FOAvip The clinical reality of cell therapy for heart disease dates back to the 1990s, when autologous skeletal myoblasts were first transplanted into failing hearts during open-chest surgery. Since then, the focus has shifted to bone marrow-derived cells and, more recently, cells extracted from the heart itself. While progress has been nonlinear and often disheartening, the field has nevertheless made remarkable progress. Six major breakthroughs are notable: 1) The establishment of safety with intracoronary delivery; 2) The demonstration that therapeutic regeneration is possible; 3) The rise of allogeneic cell therapy; 4) The impact of increasing mechanistic insights; 5) Glimmers of clinical efficacy; and 6) The progression to phase 2&3 studies. Here I review these landmark developments individually in some detail. Collectively, I conclude that the field has reached a new phase of maturity where the prospect of clinical impact is increasingly imminent. Twit Text FOAVip Breakthroughs in Cell Therapy for Heart Disease: Focus on Cardiosphere-Derived Cells ????Mayo Clin Proc http://www.kidney.de/pget.php?&tw=1&pmid=24943699 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24943699 #FOAvip English Wikipedia <ref>{{Cite pmid|24943699}}</ref> Breakthroughs in Cell Therapy for Heart Disease: Focus on Cardiosphere-Derived Cells #MMPMID24943699 Marbán E Mayo Clin Proc 2014[Jun]; 89 (6): 850-8 PMID24943699show ga The clinical reality of cell therapy for heart disease dates back to the 1990s, when autologous skeletal myoblasts were first transplanted into failing hearts during open-chest surgery. Since then, the focus has shifted to bone marrow-derived cells and, more recently, cells extracted from the heart itself. While progress has been nonlinear and often disheartening, the field has nevertheless made remarkable progress. Six major breakthroughs are notable: 1) The establishment of safety with intracoronary delivery; 2) The demonstration that therapeutic regeneration is possible; 3) The rise of allogeneic cell therapy; 4) The impact of increasing mechanistic insights; 5) Glimmers of clinical efficacy; and 6) The progression to phase 2&3 studies. Here I review these landmark developments individually in some detail. Collectively, I conclude that the field has reached a new phase of maturity where the prospect of clinical impact is increasingly imminent. äBreakthroughs in Cell Therapy for Heart Disease: Focus on Cardiosphere(epmc).pdf DeepDyve Pubget Overpricing