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10.1074/jbc.M114.556365

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suck abstract from ncbi


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pmid24920670      J+Biol+Chem 2014 ; 289 (30): 21163-80
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  • RNA Granule Assembly and Disassembly Modulated by Nuclear Factor Associated with Double-stranded RNA 2 and Nuclear Factor 45* #MMPMID24920670
  • Shiina N; Nakayama K
  • J Biol Chem 2014[Jul]; 289 (30): 21163-80 PMID24920670show ga
  • Background: RNA granules are associated with translational control and neurodegenerative disease.Results: Nuclear factor associated with dsRNA 2 (NFAR2) enhances RNA granule assembly through two domains, one of which is antagonized by nuclear factor 45 (NF45).Conclusion: NFAR2 and NF45 play novel regulatory roles in RNA granule assembly and disassembly.Significance: Mechanisms of RNA granule assembly and disassembly are the basis for understanding translational control and neurodegenerative disease.
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