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10.1074/jbc.M114.567271 http://scihub22266oqcxt.onion/10.1074/jbc.M114.567271 C4110255!4110255!24928508     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Biol+Chem 2014 ; 289 (30): 20435-46 Nephropedia Template TP {{tp|p=24928508|t=2014. Low Concentrations of Metformin Suppress Glucose Production in Hepatocytes through AMP-activated Protein Kinase (AMPK)*? |pdf=|usr=}}{{24928508}} gab.com Text Low Concentrations of Metformin Suppress Glucose Production in Hepatocytes through AMP-activated Protein Kinase (AMPK)* JO: J Biol Chem http://www.kidney.de/pget.php?&tw=1&pmid=24928508 #FOAvip Background: Whether suppression of glucose production by metformin is through AMPK-dependent inhibition of gluconeogenic gene expression remains controversial.Results: Metformin inhibits gluconeogenic gene expression in hepatocytes.Conclusion: Low metformin concentrations found in the portal vein suppress glucose production via AMPK-dependent mechanism.Significance: The hyperglucagonemia of diabetes mellitus decreases metformin suppression of glucose production through a PKA-mediated phosphorylation of the AMPK ? subunit at Ser-485/497. Twit Text FOAVip Low Concentrations of Metformin Suppress Glucose Production in Hepatocytes through AMP-activated Protein Kinase (AMPK)* ????J Biol Chem http://www.kidney.de/pget.php?&tw=1&pmid=24928508 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24928508 #FOAvip English Wikipedia <ref>{{Cite pmid|24928508}}</ref> Low Concentrations of Metformin Suppress Glucose Production in Hepatocytes through AMP-activated Protein Kinase (AMPK)*? #MMPMID24928508 Cao J; Meng S; Chang E; Beckwith-Fickas K; Xiong L; Cole RN; Radovick S; Wondisford FE; He L J Biol Chem 2014[Jul]; 289 (30): 20435-46 PMID24928508show ga Background: Whether suppression of glucose production by metformin is through AMPK-dependent inhibition of gluconeogenic gene expression remains controversial.Results: Metformin inhibits gluconeogenic gene expression in hepatocytes.Conclusion: Low metformin concentrations found in the portal vein suppress glucose production via AMPK-dependent mechanism.Significance: The hyperglucagonemia of diabetes mellitus decreases metformin suppression of glucose production through a PKA-mediated phosphorylation of the AMPK ? subunit at Ser-485/497. äLow Concentrations of Metformin Suppress Glucose Production in Hepatoc(epmc).pdf DeepDyve Pubget Overpricing