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10.1016/j.molcel.2014.05.015 http://scihub22266oqcxt.onion/10.1016/j.molcel.2014.05.015 C4103691!4103691!24905005     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=24905005&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Mol+Cell 2014 ; 54 (5): 716-27 Nephropedia Template TP {{tp|p=24905005|t=2014. Cancer epigenetics: Tumor Heterogeneity, Plasticity of Stem-like States, and Drug Resistance |pdf=|usr=}}{{24905005}} gab.com Text Cancer epigenetics: Tumor Heterogeneity, Plasticity of Stem-like States, and Drug Resistance JO: Mol Cell http://www.kidney.de/pget.php?&tw=1&pmid=24905005 #FOAvip The existence of sub-populations of cells in cancers with increased tumor initiating capacities and self-renewal potential, often termed ?cancer stem cells?, is a much discussed and key area of cancer biology. Such cellular heterogeneity is very important due to its impact on therapy and especially states of treatment resistance. A major question is whether there is plasticity for evolution of these cell states during tumorigenesis which can involve movement between cell populations in a reversible fashion. In this review, we discuss the possible role of epigenetic abnormalities, as well as genetic alterations in such dynamics, and in the creation of cellular heterogeneity in cancers of all types. Twit Text FOAVip Cancer epigenetics: Tumor Heterogeneity, Plasticity of Stem-like States, and Drug Resistance ????Mol Cell http://www.kidney.de/pget.php?&tw=1&pmid=24905005 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24905005 #FOAvip English Wikipedia <ref>{{Cite pmid|24905005}}</ref> Cancer epigenetics: Tumor Heterogeneity, Plasticity of Stem-like States, and Drug Resistance #MMPMID24905005 Easwaran H; Tsai HC; Baylin SB Mol Cell 2014[Jun]; 54 (5): 716-27 PMID24905005show ga The existence of sub-populations of cells in cancers with increased tumor initiating capacities and self-renewal potential, often termed ?cancer stem cells?, is a much discussed and key area of cancer biology. Such cellular heterogeneity is very important due to its impact on therapy and especially states of treatment resistance. A major question is whether there is plasticity for evolution of these cell states during tumorigenesis which can involve movement between cell populations in a reversible fashion. In this review, we discuss the possible role of epigenetic abnormalities, as well as genetic alterations in such dynamics, and in the creation of cellular heterogeneity in cancers of all types. äCancer epigenetics: Tumor Heterogeneity, Plasticity of Stem-like State(epmc).pdf DeepDyve Pubget Overpricing