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2014 ; 10
(4
): 369-76
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Research and clinical applications of optical coherence tomography in invasive
cardiology: a review
#MMPMID24893934
Vignali L
; Solinas E
; Emanuele E
Curr Cardiol Rev
2014[Nov]; 10
(4
): 369-76
PMID24893934
show ga
In cardiology, optical coherence tomography (OCT) is an invasive imaging
technique based on the principle of light coherence. This system was developed to
obtain three-dimensional high resolution images to examine coronary artery normal
and/or pathological structure. This technique replaces the ultrasound used by its
main alternative procedure, intravascular ultrasound, by a near-infrared light
source. Acute coronary syndromes due to atherosclerotic vascular disease are the
leading cause of mortality in developed and developing countries. As a
consequence, intravascular imaging systems became an important area of research
and 1991 marks the first use of OCT in coronary artery observations. Since its
first appearance in invasive cardiology, OCT maintains a strong presence in the
research environments for the identification of vulnerable plaques, as it is able
to overcome difficulties presented by other techniques such as virtual
intravascular ultrasound, near-infrared spectroscopy, and histology. Moreover,
OCT is increasingly being used in the clinical practice as a guide during
coronary interventions and in the assessment of vascular response after coronary
stent implantation. This review focuses on the relevance of OCT in research and
clinical applications in the field of invasive cardiology and discusses the
future directions of the field.