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10.1016/j.jcrs.2013.09.022 http://scihub22266oqcxt.onion/10.1016/j.jcrs.2013.09.022 C4096125!4096125 !24751145     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\24751145 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       J+Cataract+Refract+Surg 2014 ; 40 (6 ): 1021-31 Nephropedia Template TP {{tp|p=24751145 |t=2014. Spatially heterogeneous corneal mechanical responses before and after riboflavin-ultraviolet-A crosslinking |pdf=|usr=}}{{24751145 }} gab.com Text Spatially heterogeneous corneal mechanical responses before and after riboflavin-ultraviolet-A crosslinking JO: J Cataract Refract Surg http://www.kidney.de/pget.php?&tw=1&pmid=24751145 #FOAvip PURPOSE: To determine the heterogeneous through-thickness strains in the cornea at physiologic intraocular pressures before and after corneal collagen crosslinking (CXL) using noninvasive ultrasound. SETTING: Department of Biomedical Engineering, Ohio State University, Columbus, Ohio, USA. DESIGN: Experimental study. METHODS: Sixteen paired canine corneoscleral shells were divided into 2 groups. The CXL group completed a standard CXL protocol using riboflavin-ultraviolet-A (UVA) irradiation. The control group was given an identical treatment except UVA irradiation. Ultrasound scans (at 55 MHz) of the cornea were obtained before and after treatment as the corneoscleral shell was inflated from 5 mm Hg to 45 mm Hg to calculate the distributive through-thickness strains in the cornea. The mean radial and tangential strains of the whole cornea layer, as well as those of the anterior, middle, and posterior thirds of the cornea, were compared before and after treatment in the control group and CXL group using linear mixed models with repeated measures. RESULTS: Significant reductions in tangential and radial strains occurred in the CXL group (P=.003 and P=.0025, respectively) but not the control group (P=.08 and P=.63, respectively). The anterior third had the smallest strains in all pretreated corneas (P<.001) and posttreated corneas (CXL group, P=.023; control group, P=.01). CONCLUSIONS: Ultrasound speckle tracking showed heterogeneous strain distributions through the cornea and confirmed that CXL results in a stiffer corneal response (ie, smaller strains during physiologic loadings). This technique may provide a clinical tool to quantify the biomechanical effects of CXL. FINANCIAL DISCLOSURE: No author has a financial or proprietary interest in any material or method mentioned. Twit Text FOAVip Spatially heterogeneous corneal mechanical responses before and after riboflavin-ultraviolet-A crosslinking ????J Cataract Refract Surg http://www.kidney.de/pget.php?&tw=1&pmid=24751145 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24751145 #FOAvip English Wikipedia <ref>{{Cite pmid|24751145 }}</ref> Spatially heterogeneous corneal mechanical responses before and after riboflavin-ultraviolet-A crosslinking #MMPMID24751145 Palko JR ; Tang J ; Cruz Perez B ; Pan X ; Liu J J Cataract Refract Surg 2014[Jun]; 40 (6 ): 1021-31 PMID24751145 show ga PURPOSE: To determine the heterogeneous through-thickness strains in the cornea at physiologic intraocular pressures before and after corneal collagen crosslinking (CXL) using noninvasive ultrasound. SETTING: Department of Biomedical Engineering, Ohio State University, Columbus, Ohio, USA. DESIGN: Experimental study. METHODS: Sixteen paired canine corneoscleral shells were divided into 2 groups. The CXL group completed a standard CXL protocol using riboflavin-ultraviolet-A (UVA) irradiation. The control group was given an identical treatment except UVA irradiation. Ultrasound scans (at 55 MHz) of the cornea were obtained before and after treatment as the corneoscleral shell was inflated from 5 mm Hg to 45 mm Hg to calculate the distributive through-thickness strains in the cornea. The mean radial and tangential strains of the whole cornea layer, as well as those of the anterior, middle, and posterior thirds of the cornea, were compared before and after treatment in the control group and CXL group using linear mixed models with repeated measures. RESULTS: Significant reductions in tangential and radial strains occurred in the CXL group (P=.003 and P=.0025, respectively) but not the control group (P=.08 and P=.63, respectively). The anterior third had the smallest strains in all pretreated corneas (P<.001) and posttreated corneas (CXL group, P=.023; control group, P=.01). CONCLUSIONS: Ultrasound speckle tracking showed heterogeneous strain distributions through the cornea and confirmed that CXL results in a stiffer corneal response (ie, smaller strains during physiologic loadings). This technique may provide a clinical tool to quantify the biomechanical effects of CXL. FINANCIAL DISCLOSURE: No author has a financial or proprietary interest in any material or method mentioned. |Algorithms [MESH] |Animals [MESH] |Biomechanical Phenomena/*physiology [MESH] |Collagen/*metabolism [MESH] |Corneal Stroma/diagnostic imaging/drug effects/metabolism/*physiopathology [MESH] |Cross-Linking Reagents/*pharmacology [MESH] |Dogs [MESH] |Elasticity/physiology [MESH] |Intraocular Pressure/physiology [MESH] |Microscopy, Acoustic [MESH] |Photosensitizing Agents/*pharmacology [MESH] |Riboflavin/*pharmacology [MESH] |Stress, Mechanical [MESH]Spatially heterogeneous corneal mechanical responses before and after (epmc).pdf DeepDyve Pubget Overpricing