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2014 ; 26
(10
): 1318-25
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gab.com Text
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English Wikipedia
Development of an electronic medical record-based algorithm to identify patients
with unknown HIV status
#MMPMID24779521
Felsen UR
; Bellin EY
; Cunningham CO
; Zingman BS
AIDS Care
2014[]; 26
(10
): 1318-25
PMID24779521
show ga
Individuals with unknown HIV status are at risk for undiagnosed HIV, but
practical and reliable methods for identifying these individuals have not been
described. We developed an algorithm to identify patients with unknown HIV status
using data from the electronic medical record (EMR) of a large health care
system. We developed EMR-based criteria to classify patients as having known
status (HIV-positive or HIV-negative) or unknown status and applied these
criteria to all patients seen in the affiliated health care system from 2008 to
2012. Performance characteristics of the algorithm for identifying patients with
unknown HIV status were calculated by comparing a random sample of the
algorithm's results to a reference standard medical record review. The algorithm
classifies all patients as having either known or unknown HIV status. Its
sensitivity and specificity for identifying patients with unknown status are
99.4% (95% CI: 96.5-100%) and 95.2% (95% CI: 83.8-99.4%), respectively, with
positive and negative predictive values of 98.7% (95% CI: 95.5-99.8%) and 97.6%
(95% CI: 87.1-99.1%), respectively. Using commonly available data from an EMR,
our algorithm has high sensitivity and specificity for identifying patients with
unknown HIV status. This algorithm may inform expanded HIV testing strategies
aiming to test the untested.