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10.1161/CIRCRESAHA.115.302929 http://scihub22266oqcxt.onion/10.1161/CIRCRESAHA.115.302929 C4094348!4094348!24951760     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Circ+Res 2014 ; 115 (1): 97-107 Nephropedia Template TP {{tp|p=24951760|t=2014. Heart Failure with Preserved Ejection Fraction: Molecular Pathways of the Aging Myocardium |pdf=|usr=}}{{24951760}} gab.com Text Heart Failure with Preserved Ejection Fraction: Molecular Pathways of the Aging Myocardium JO: Circ Res http://www.kidney.de/pget.php?&tw=1&pmid=24951760 #FOAvip Age-related diastolic dysfunction is a major factor in the epidemic of heart failure. In patients hospitalized with heart failure, diastolic heart failure is now as common as systolic heart failure. We now have many successful treatments for HFrEF, while specific treatment options for HFpEF patients remain elusive. The lack of treatments for HFpEF reflects our very incomplete understanding of this constellation of diseases. There are many pathophysiological factors in HFpEF, but aging appears to play an important role. Here we propose that aging of the myocardium is itself a specific pathophysiological process. New insights into the aging heart, including hormonal controls and specific molecular pathways such as microRNAs, are pointing to myocardial aging as a potentially reversible process. While the overall process of aging remains mysterious, understanding the molecular pathways of myocardial aging has never been more important. Unraveling these pathways could lead to new therapies for the enormous and growing problem of HFpEF. Twit Text FOAVip Heart Failure with Preserved Ejection Fraction: Molecular Pathways of the Aging Myocardium ????Circ Res http://www.kidney.de/pget.php?&tw=1&pmid=24951760 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24951760 #FOAvip English Wikipedia <ref>{{Cite pmid|24951760}}</ref> Heart Failure with Preserved Ejection Fraction: Molecular Pathways of the Aging Myocardium #MMPMID24951760 Loffredo FS; Nikolova AP; Pancoast JR; Lee RT Circ Res 2014[Jun]; 115 (1): 97-107 PMID24951760show ga Age-related diastolic dysfunction is a major factor in the epidemic of heart failure. In patients hospitalized with heart failure, diastolic heart failure is now as common as systolic heart failure. We now have many successful treatments for HFrEF, while specific treatment options for HFpEF patients remain elusive. The lack of treatments for HFpEF reflects our very incomplete understanding of this constellation of diseases. There are many pathophysiological factors in HFpEF, but aging appears to play an important role. Here we propose that aging of the myocardium is itself a specific pathophysiological process. New insights into the aging heart, including hormonal controls and specific molecular pathways such as microRNAs, are pointing to myocardial aging as a potentially reversible process. While the overall process of aging remains mysterious, understanding the molecular pathways of myocardial aging has never been more important. Unraveling these pathways could lead to new therapies for the enormous and growing problem of HFpEF. äHeart Failure with Preserved Ejection Fraction: Molecular Pathways of (epmc).pdf DeepDyve Pubget Overpricing