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10.1074/jbc.M113.535237

http://scihub22266oqcxt.onion/10.1074/jbc.M113.535237
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C4094049!4094049!24860090
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suck abstract from ncbi


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pmid24860090      J+Biol+Chem 2014 ; 289 (28): 19373-82
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  • Role of Glucocorticoid-induced Leucine Zipper (GILZ) in Bone Acquisition* #MMPMID24860090
  • Pan G; Cao J; Yang N; Ding K; Fan C; Xiong WC; Hamrick M; Isales CM; Shi XM
  • J Biol Chem 2014[Jul]; 289 (28): 19373-82 PMID24860090show ga
  • Background: The in vivo role of GILZ, a glucocorticoid-indicible protein, in bone acquisition is unknown.Results: Overexpression of GILZ in osteoprogenitor cells increases bone acquisition in mice.Conclusion: GILZ enhances bone acquisition by promoting marrow mesenchymal stem/progenitor cell osteogenic differentiation.Significance: GILZ may represent the first GC-responsive gene mediating the positive effect of GCs in bone.
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