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The heat shock protein-CD91 pathway mediates tumor immunosurveillance #MMPMID25050192
Zhou YJ; Binder RJ
Oncoimmunology 2014[]; 3 (ä): ä PMID25050192show ga
Tumor immunosurveillance can be readily observed in mice and humans. Here, we examine how T-cell responses are primed during tumorigenesis, a condition in which immunostimulatory antigens are extraordinarily scarce. We recently demonstrated that the HSP-CD91 pathway is indispensable for antigen cross-presentation, and thus immunosurveillance, in cancer.