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10.1136/neurintsurg-2013-010973 http://scihub22266oqcxt.onion/10.1136/neurintsurg-2013-010973 C4090292!4090292 !24353330     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=24353330 &cmd=llinks): Failed to open stream: HTTP request failed! 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Correlation of AOL recanalization, TIMI reperfusion and TICI reperfusion with infarct growth and clinical outcome |pdf=|usr=}}{{24353330 }} gab.com Text Correlation of AOL recanalization, TIMI reperfusion and TICI reperfusion with infarct growth and clinical outcome JO: J Neurointerv Surg http://www.kidney.de/pget.php?&tw=1&pmid=24353330 #FOAvip OBJECTIVE: To understand how three commonly used measures of endovascular therapy correlate with clinical outcome and infarct growth. METHODS: Prospectively enrolled patients underwent baseline MRI and started endovascular therapy within 12?h of stroke onset. The final angiogram was given a primary arterial occlusive lesion (AOL) recanalization score (0-3), a Thrombolysis in Myocardial Infarction (TIMI) score (0-3) and a Thrombolysis in Cerebral Infarction (TICI) score (0-3). The scores were dichotomized into poor revascularization (AOL 0-2, TIMI 0-1 and TICI 0-2a) versus good revascularization (AOL 3, TIMI 2-3, TICI 2b-3). Patients were classified according to whether or not they had target mismatch (TMM). Good outcome was defined as a 90-day modified Rankin Scale score of 0-2. RESULTS: Endovascular treatment was attempted in 100. A good outcome was achieved in 57% of patients with a TICI score of 2b-3 and in 24% of patients with a TICI score of 0-2a (p=0.001). Patients with TIMI scores of 2-3 and an AOL score of 3 had lower rates of good outcome (44% and 47%, respectively), which were not significantly better than those with TIMI scores of 0-1 or AOL scores of 0-2. In patients with TMM, these rates of good outcome improved with all the scoring systems and were significantly better for TIMI and TICI scores. Patients with a TICI score of 2a had rates of good functional outcome and lesion growth which were not different from those with TICI scores of 0-1 but were significantly worse than those with TICI scores of 2b-3. CONCLUSIONS: TIMI 2-3 and TICI 2b-3 reperfusion scores demonstrated improved outcome in patients with tissue mismatch with a small infarct core and a larger hypoperfused region but AOL scores did not. Patients with a TICI score of 2a had a poorer outcome and more lesion growth than those with TICI scores of 2b-3. Twit Text FOAVip Correlation of AOL recanalization, TIMI reperfusion and TICI reperfusion with infarct growth and clinical outcome ????J Neurointerv Surg http://www.kidney.de/pget.php?&tw=1&pmid=24353330 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24353330 #FOAvip English Wikipedia <ref>{{Cite pmid|24353330 }}</ref> Correlation of AOL recanalization, TIMI reperfusion and TICI reperfusion with infarct growth and clinical outcome #MMPMID24353330 Marks MP ; Lansberg MG ; Mlynash M ; Kemp S ; McTaggart R ; Zaharchuk G ; Bammer R ; Albers GW J Neurointerv Surg 2014[Dec]; 6 (10 ): 724-8 PMID24353330 show ga OBJECTIVE: To understand how three commonly used measures of endovascular therapy correlate with clinical outcome and infarct growth. METHODS: Prospectively enrolled patients underwent baseline MRI and started endovascular therapy within 12?h of stroke onset. The final angiogram was given a primary arterial occlusive lesion (AOL) recanalization score (0-3), a Thrombolysis in Myocardial Infarction (TIMI) score (0-3) and a Thrombolysis in Cerebral Infarction (TICI) score (0-3). The scores were dichotomized into poor revascularization (AOL 0-2, TIMI 0-1 and TICI 0-2a) versus good revascularization (AOL 3, TIMI 2-3, TICI 2b-3). Patients were classified according to whether or not they had target mismatch (TMM). Good outcome was defined as a 90-day modified Rankin Scale score of 0-2. RESULTS: Endovascular treatment was attempted in 100. A good outcome was achieved in 57% of patients with a TICI score of 2b-3 and in 24% of patients with a TICI score of 0-2a (p=0.001). Patients with TIMI scores of 2-3 and an AOL score of 3 had lower rates of good outcome (44% and 47%, respectively), which were not significantly better than those with TIMI scores of 0-1 or AOL scores of 0-2. In patients with TMM, these rates of good outcome improved with all the scoring systems and were significantly better for TIMI and TICI scores. Patients with a TICI score of 2a had rates of good functional outcome and lesion growth which were not different from those with TICI scores of 0-1 but were significantly worse than those with TICI scores of 2b-3. CONCLUSIONS: TIMI 2-3 and TICI 2b-3 reperfusion scores demonstrated improved outcome in patients with tissue mismatch with a small infarct core and a larger hypoperfused region but AOL scores did not. Patients with a TICI score of 2a had a poorer outcome and more lesion growth than those with TICI scores of 2b-3. |*Endovascular Procedures/methods/standards [MESH] |Aged [MESH] |Cerebral Infarction/*surgery [MESH] |Cerebral Revascularization/methods/standards [MESH] |Female [MESH] |Humans [MESH] |Magnetic Resonance Imaging, Interventional [MESH] |Male [MESH] |Prospective Studies [MESH] |Severity of Illness Index [MESH]Correlation of AOL recanalization, TIMI reperfusion and TICI reperfusi(epmc).pdf DeepDyve Pubget Overpricing