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10.1016/j.biocel.2014.03.029 http://scihub22266oqcxt.onion/10.1016/j.biocel.2014.03.029 C4083841!4083841!24718374     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Biochem+Cell+Biol 2014 ; 51 (ä): 89-92 Nephropedia Template TP {{tp|p=24718374|t=2014. ?-Thalassemia and Polycythemia vera: targeting chronic stress erythropoiesis |pdf=|usr=}}{{24718374}} gab.com Text -Thalassemia and Polycythemia vera: targeting chronic stress erythropoiesis JO: Int J Biochem Cell Biol http://www.kidney.de/pget.php?&tw=1&pmid=24718374 #FOAvip ?-thalassemia and Polycythemia vera are genetic disorders which affect the synthesis of red blood cells, also referred to as erythropoiesis. Although essentially different in clinical presentation ? patients with ?-thalassemia have an impairment in ?-globin synthesis leading to defective erythrocytes and anemia, while patients with Polycythemia vera present with high hemoglobin levels because of excessive red blood cell synthesis ? both pathologies may characterized by lasting high erythropoietic activity, i.e. chronic stress erythropoiesis. In both diseases, therapeutic strategies targeting chronic stress erythropoiesis may improve the address phenotype and prevent secondary pathology, such as iron overload. The current review will address the basic concepts of these strategies to reduce chronic stress erythropoiesis, which may have significant clinical implications in the near future. Twit Text FOAVip -Thalassemia and Polycythemia vera: targeting chronic stress erythropoiesis ????Int J Biochem Cell Biol http://www.kidney.de/pget.php?&tw=1&pmid=24718374 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24718374 #FOAvip English Wikipedia <ref>{{Cite pmid|24718374}}</ref> ?-Thalassemia and Polycythemia vera: targeting chronic stress erythropoiesis #MMPMID24718374 Crielaard BJ; Rivella S Int J Biochem Cell Biol 2014[Jun]; 51 (ä): 89-92 PMID24718374show ga ?-thalassemia and Polycythemia vera are genetic disorders which affect the synthesis of red blood cells, also referred to as erythropoiesis. Although essentially different in clinical presentation ? patients with ?-thalassemia have an impairment in ?-globin synthesis leading to defective erythrocytes and anemia, while patients with Polycythemia vera present with high hemoglobin levels because of excessive red blood cell synthesis ? both pathologies may characterized by lasting high erythropoietic activity, i.e. chronic stress erythropoiesis. In both diseases, therapeutic strategies targeting chronic stress erythropoiesis may improve the address phenotype and prevent secondary pathology, such as iron overload. The current review will address the basic concepts of these strategies to reduce chronic stress erythropoiesis, which may have significant clinical implications in the near future. ä?-Thalassemia and Polycythemia vera: targeting chronic stress erythrop(epmc).pdf DeepDyve Pubget Overpricing