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10.1111/imm.12272 http://scihub22266oqcxt.onion/10.1111/imm.12272 C4080950!4080950!24597601     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Immunology 2014 ; 142 (3): 347-53 Nephropedia Template TP {{tp|p=24597601|t=2014. Sphingosine-1-phosphate receptor 1 signalling in T cells: trafficking and beyond |pdf=|usr=}}{{24597601}} gab.com Text Sphingosine-1-phosphate receptor 1 signalling in T cells: trafficking and beyond JO: Immunology http://www.kidney.de/pget.php?&tw=1&pmid=24597601 #FOAvip Sphingosine-1-phosphate (S1P) is a lipid second messenger that signals via five G protein-coupled receptors (S1P1?5). S1P receptor (S1PR) signalling is associated with a wide variety of physiological processes including lymphocyte biology, their recirculation and determination of T-cell phenotypes. The effect of FTY720 (Fingolimod, Gilenya?) to regulate lymphocyte egress and to ameliorate paralysis in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis led to the use of FTY720 as a first-line oral agent for treatment of relapsing?remitting multiple sclerosis. However, a significant body of research suggests that S1P signalling may participate in diverse immune regulatory functions other than lymphocyte trafficking. This review article discusses the current knowledge of S1P signalling in the fate and function of T regulatory, T helper type 17 and memory T cells in health and disease. Twit Text FOAVip Sphingosine-1-phosphate receptor 1 signalling in T cells: trafficking and beyond ????Immunology http://www.kidney.de/pget.php?&tw=1&pmid=24597601 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24597601 #FOAvip English Wikipedia <ref>{{Cite pmid|24597601}}</ref> Sphingosine-1-phosphate receptor 1 signalling in T cells: trafficking and beyond #MMPMID24597601 Garris CS; Blaho VA; Hla T; Han MH Immunology 2014[Jul]; 142 (3): 347-53 PMID24597601show ga Sphingosine-1-phosphate (S1P) is a lipid second messenger that signals via five G protein-coupled receptors (S1P1?5). S1P receptor (S1PR) signalling is associated with a wide variety of physiological processes including lymphocyte biology, their recirculation and determination of T-cell phenotypes. The effect of FTY720 (Fingolimod, Gilenya?) to regulate lymphocyte egress and to ameliorate paralysis in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis led to the use of FTY720 as a first-line oral agent for treatment of relapsing?remitting multiple sclerosis. However, a significant body of research suggests that S1P signalling may participate in diverse immune regulatory functions other than lymphocyte trafficking. This review article discusses the current knowledge of S1P signalling in the fate and function of T regulatory, T helper type 17 and memory T cells in health and disease. äSphingosine-1-phosphate receptor 1 signalling in T cells: trafficking (epmc).pdf DeepDyve Pubget Overpricing