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10.1152/ajprenal.00547.2013 http://scihub22266oqcxt.onion/10.1152/ajprenal.00547.2013 C4080159!4080159!24808539     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Am+J+Physiol+Renal+Physiol 2014 ; 307 (1): F64-74 Nephropedia Template TP {{tp|p=24808539|t=2014. Role of medullary progenitor cells in epithelial cell migration and proliferation |pdf=|usr=}}{{24808539}} gab.com Text Role of medullary progenitor cells in epithelial cell migration and proliferation JO: Am J Physiol Renal Physiol http://www.kidney.de/pget.php?&tw=1&pmid=24808539 #FOAvip This study is aimed at characterizing medullary interstitial progenitor cells and to examine their capacity to induce tubular epithelial cell migration and proliferation. We have isolated a progenitor cell side population from a primary medullary interstitial cell line. We show that the medullary progenitor cells (MPCs) express CD24, CD44, CXCR7, CXCR4, nestin, and PAX7. MPCs are CD34 negative, which indicates that they are not bone marrow-derived stem cells. MPCs survive >50 passages, and when grown in epithelial differentiation medium develop phenotypic characteristics of epithelial cells. Inner medulla collecting duct (IMCD3) cells treated with conditioned medium from MPCs show significantly accelerated cell proliferation and migration. Conditioned medium from PGE2-treated MPCs induce tubule formation in IMCD3 cells grown in 3D Matrigel. Moreover, most of the MPCs express the pericyte marker PDGFR-b. Our study shows that the medullary interstitium harbors a side population of progenitor cells that can differentiate to epithelial cells and can stimulate tubular epithelial cell migration and proliferation. The findings of this study suggest that medullary pericyte/progenitor cells may play a critical role in collecting duct cell injury repair. Twit Text FOAVip Role of medullary progenitor cells in epithelial cell migration and proliferation ????Am J Physiol Renal Physiol http://www.kidney.de/pget.php?&tw=1&pmid=24808539 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24808539 #FOAvip English Wikipedia <ref>{{Cite pmid|24808539}}</ref> Role of medullary progenitor cells in epithelial cell migration and proliferation #MMPMID24808539 Chen D; Chen Z; Zhang Y; Park C; Al-Omari A; Moeckel GW Am J Physiol Renal Physiol 2014[Jul]; 307 (1): F64-74 PMID24808539show ga This study is aimed at characterizing medullary interstitial progenitor cells and to examine their capacity to induce tubular epithelial cell migration and proliferation. We have isolated a progenitor cell side population from a primary medullary interstitial cell line. We show that the medullary progenitor cells (MPCs) express CD24, CD44, CXCR7, CXCR4, nestin, and PAX7. MPCs are CD34 negative, which indicates that they are not bone marrow-derived stem cells. MPCs survive >50 passages, and when grown in epithelial differentiation medium develop phenotypic characteristics of epithelial cells. Inner medulla collecting duct (IMCD3) cells treated with conditioned medium from MPCs show significantly accelerated cell proliferation and migration. Conditioned medium from PGE2-treated MPCs induce tubule formation in IMCD3 cells grown in 3D Matrigel. Moreover, most of the MPCs express the pericyte marker PDGFR-b. Our study shows that the medullary interstitium harbors a side population of progenitor cells that can differentiate to epithelial cells and can stimulate tubular epithelial cell migration and proliferation. The findings of this study suggest that medullary pericyte/progenitor cells may play a critical role in collecting duct cell injury repair. äRole of medullary progenitor cells in epithelial cell migration and pr(epmc).pdf DeepDyve Pubget Overpricing