Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1016/j.cmet.2014.03.027 http://scihub22266oqcxt.onion/10.1016/j.cmet.2014.03.027 C4079747!4079747!24794975     free     free     free       Cell+Metab 2014 ; 20 (1): 26-40 Nephropedia Template TP {{tp|p=24794975|t=2014. Transcriptional coregulators: fine-tuning metabolism |pdf=|usr=}}{{24794975}} gab.com Text Transcriptional coregulators: fine-tuning metabolism JO: Cell Metab http://www.kidney.de/pget.php?&tw=1&pmid=24794975 #FOAvip Metabolic homeostasis requires that cellular energy levels are adapted to environmental cues. This adaptation is largely regulated at the transcriptional level, through the interaction between transcription factors, coregulators, and the basal transcriptional machinery. Coregulators, which function both as metabolic sensors and transcriptional effectors, are ideally positioned to synchronize metabolic pathways to environmental stimuli. The balance between inhibitory actions of corepressors and stimulatory effects of coactivators enables the fine-tuning of metabolic processes. The tight regulation opens therapeutic opportunities to manage metabolic dysfunction, by directing the activity of cofactors towards specific transcription factors, pathways, or cells/tissues, thereby restoring whole body metabolic homeostasis. Twit Text FOAVip Transcriptional coregulators: fine-tuning metabolism ????Cell Metab http://www.kidney.de/pget.php?&tw=1&pmid=24794975 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24794975 #FOAvip English Wikipedia <ref>{{Cite pmid|24794975}}</ref> Transcriptional coregulators: fine-tuning metabolism #MMPMID24794975 Mouchiroud L; Eichner LJ; Shaw R; Auwerx J Cell Metab 2014[Jul]; 20 (1): 26-40 PMID24794975show ga Metabolic homeostasis requires that cellular energy levels are adapted to environmental cues. This adaptation is largely regulated at the transcriptional level, through the interaction between transcription factors, coregulators, and the basal transcriptional machinery. Coregulators, which function both as metabolic sensors and transcriptional effectors, are ideally positioned to synchronize metabolic pathways to environmental stimuli. The balance between inhibitory actions of corepressors and stimulatory effects of coactivators enables the fine-tuning of metabolic processes. The tight regulation opens therapeutic opportunities to manage metabolic dysfunction, by directing the activity of cofactors towards specific transcription factors, pathways, or cells/tissues, thereby restoring whole body metabolic homeostasis. äTranscriptional coregulators: fine-tuning metabolism (epmc).pdf DeepDyve Pubget Overpricing