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10.1039/C4AY00320A http://scihub22266oqcxt.onion/10.1039/C4AY00320A C4078893!4078893!24999374     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Anal+Methods 2014 ; 6 (14): 5001-7 Nephropedia Template TP {{tp|p=24999374|t=2014. MALDI-Ion Mobility Mass Spectrometry of Lipids in Negative Ion Mode |pdf=|usr=}}{{24999374}} gab.com Text MALDI-Ion Mobility Mass Spectrometry of Lipids in Negative Ion Mode JO: Anal Methods http://www.kidney.de/pget.php?&tw=1&pmid=24999374 #FOAvip Profiling and imaging MALDI mass spectrometry (MS) allows detection and localization of biomolecules in tissue, of which lipids are a major component. However, due to the in situ nature of this technique, complexity of tissue and need for a chemical matrix, the recorded signal is complex and can be difficult to assign. Ion mobility adds a dimension that provides coarse shape information, separating isobaric lipids, peptides, and oligonucleotides along distinct familial trend lines before mass analysis. Previous work using MALDI-ion mobility mass spectrometry to analyze and image lipids has been conducted mainly in positive ion mode, although several lipid classes ionize preferentially in negative ion mode. This work highlights recent data acquired in negative ion mode to detect glycerophosphoethanolamines (PEs), glycerophosphoserines (PSs), glycerophosphoglycerols (PGs), glycerolphosphoinositols (PIs), glycerophosphates (PAs), sulfatides (STs), and gangliosides from standard tissue extracts and directly from mouse brain tissue. In particular, this study focused on changes in ion mobility based upon lipid head groups, composition of radyl chain (# of carbons and double bonds), diacyl versus plasmalogen species, and hydroxylation of species. Finally, a MALDI-ion mobility imaging run was conducted in negative ion mode, resulting in the successful ion mapping of several lipid species. Twit Text FOAVip MALDI-Ion Mobility Mass Spectrometry of Lipids in Negative Ion Mode ????Anal Methods http://www.kidney.de/pget.php?&tw=1&pmid=24999374 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24999374 #FOAvip English Wikipedia <ref>{{Cite pmid|24999374}}</ref> MALDI-Ion Mobility Mass Spectrometry of Lipids in Negative Ion Mode #MMPMID24999374 Jackson SN; Barbacci D; Egan T; Lewis EK; Schultz JA; Woods AS Anal Methods 2014[Jul]; 6 (14): 5001-7 PMID24999374show ga Profiling and imaging MALDI mass spectrometry (MS) allows detection and localization of biomolecules in tissue, of which lipids are a major component. However, due to the in situ nature of this technique, complexity of tissue and need for a chemical matrix, the recorded signal is complex and can be difficult to assign. Ion mobility adds a dimension that provides coarse shape information, separating isobaric lipids, peptides, and oligonucleotides along distinct familial trend lines before mass analysis. Previous work using MALDI-ion mobility mass spectrometry to analyze and image lipids has been conducted mainly in positive ion mode, although several lipid classes ionize preferentially in negative ion mode. This work highlights recent data acquired in negative ion mode to detect glycerophosphoethanolamines (PEs), glycerophosphoserines (PSs), glycerophosphoglycerols (PGs), glycerolphosphoinositols (PIs), glycerophosphates (PAs), sulfatides (STs), and gangliosides from standard tissue extracts and directly from mouse brain tissue. In particular, this study focused on changes in ion mobility based upon lipid head groups, composition of radyl chain (# of carbons and double bonds), diacyl versus plasmalogen species, and hydroxylation of species. Finally, a MALDI-ion mobility imaging run was conducted in negative ion mode, resulting in the successful ion mapping of several lipid species. äMALDI-Ion Mobility Mass Spectrometry of Lipids in Negative Ion Mode (epmc).pdf DeepDyve Pubget Overpricing