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10.1016/j.tem.2014.05.002 http://scihub22266oqcxt.onion/10.1016/j.tem.2014.05.002 C4077945!4077945!24895003     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Trends+Endocrinol+Metab 2014 ; 25 (7): 356-63 Nephropedia Template TP {{tp|p=24895003|t=2014. Lipid metabolites as metabolic messengers in inter-organ communication |pdf=|usr=}}{{24895003}} gab.com Text Lipid metabolites as metabolic messengers in inter-organ communication JO: Trends Endocrinol Metab http://www.kidney.de/pget.php?&tw=1&pmid=24895003 #FOAvip Metabolic homeostasis is achieved through coordinated regulation across several tissues. Studies using mouse genetic models have shown that perturbation of specific pathways of lipid metabolism in metabolically active tissues impacts systemic metabolic homeostasis. The use of metabolomic technologies combined with genetic models has helped identify several potential lipid mediators that serve as metabolic messengers to communicate energy status and modulate substrate utilization among tissues. When provided exogenously, these lipid metabolites exhibit biological effects on glucose and lipid metabolism, implicating a therapeutic potential for treating metabolic diseases. In this review, we will summarize recent advances in inter-organ communication through novel mechanisms with a focus on lipid mediators synthesized de novo or derived from dietary sources and discuss challenges and future directions. Twit Text FOAVip Lipid metabolites as metabolic messengers in inter-organ communication ????Trends Endocrinol Metab http://www.kidney.de/pget.php?&tw=1&pmid=24895003 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24895003 #FOAvip English Wikipedia <ref>{{Cite pmid|24895003}}</ref> Lipid metabolites as metabolic messengers in inter-organ communication #MMPMID24895003 Liu S; Alexander RK; Lee CH Trends Endocrinol Metab 2014[Jul]; 25 (7): 356-63 PMID24895003show ga Metabolic homeostasis is achieved through coordinated regulation across several tissues. Studies using mouse genetic models have shown that perturbation of specific pathways of lipid metabolism in metabolically active tissues impacts systemic metabolic homeostasis. The use of metabolomic technologies combined with genetic models has helped identify several potential lipid mediators that serve as metabolic messengers to communicate energy status and modulate substrate utilization among tissues. When provided exogenously, these lipid metabolites exhibit biological effects on glucose and lipid metabolism, implicating a therapeutic potential for treating metabolic diseases. In this review, we will summarize recent advances in inter-organ communication through novel mechanisms with a focus on lipid mediators synthesized de novo or derived from dietary sources and discuss challenges and future directions. äLipid metabolites as metabolic messengers in inter-organ communication(epmc).pdf DeepDyve Pubget Overpricing