Systems approaches to coronavirus pathogenesis #MMPMID24842079
Schäfer A; Baric RS; Ferris MT
Curr Opin Virol 2014[Jun]; 6 (ä): 61-9 PMID24842079show ga
?Coronaviruses (CoV) emergence has caused two major outbreaks within the past decade.?Systems biology has identified host components critical to CoV pathogenesis.?CoV disease is influenced by host genetic polymorphisms.?Systems genetics drives a broader insight into viral disease outcomes.?Both approaches provide transitions into therapeutics and human disease.