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2014 ; 18
(3
): 154
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Renal recovery after acute kidney injury: choice of initial renal replacement
therapy modality still matters
#MMPMID25042793
Schneider AG
; Bagshaw SM
Crit Care
2014[Jun]; 18
(3
): 154
PMID25042793
show ga
Renal replacement therapy can be applied either in an intermittent fashion or in
a continuous fashion in severe acute kidney injury. To date, no modality has been
shown to consistently improve patient survival. In the study recently reported by
Sun and colleagues, continuous application of renal replacement therapy was
associated with improved renal recovery, defined by lower risk of long-term need
for chronic dialysis therapy. This association between nonrecovery and
intermittent renal replacement therapy may be explained by a higher rate of
hypotensive episodes and the lower capacity for fluid removal during the first 72
hours of therapy. Altogether, this study adds to the growing body of evidence to
suggest improved likelihood of recovery of kidney function in critically ill
survivors of AKI with continuous modalities for renal replacement therapy.