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10.1186/cc13924 http://scihub22266oqcxt.onion/10.1186/cc13924 C4075119!4075119!25041977     free     free     free       Crit+Care 2014 ; 18 (3): 152 Nephropedia Template TP {{tp|p=25041977|t=2014. Adrenomedullin: a vasodilator to treat sepsis?|pdf=|usr=}}{{25041977}} gab.com Text Adrenomedullin: a vasodilator to treat sepsis JO: Crit Care http://www.kidney.de/pget.php?&tw=1&pmid=25041977 #FOAvip Adrenomedullin is a vasodilatory polypeptide with pleiotropic effects secreted by various organs. Adrenomedullin is produced first as a prepropeptide, and then cleaved into mature adrenomedullin and mid-regional proadrenomedullin. Whereas levels of the latter have been shown to correlate with severity of sepsis and carry prognostic value, adrenomedullin plays a role in vascular tone homeostasis. In the previous issue of Critical Care, the infusion of exogenous adrenomedullin is suggested to protect against increased lung endothelial permeability and end-organ dysfunction in a model of pneumococcal pneumonia in mechanically ventilated mice, possibly by stabilizing vascular endothelia. Since adrenomedullin is a strong vasodilatory molecule, further studies are needed to evaluate its potential as a future treatment of sepsis. Twit Text FOAVip Adrenomedullin: a vasodilator to treat sepsis ????Crit Care http://www.kidney.de/pget.php?&tw=1&pmid=25041977 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25041977 #FOAvip English Wikipedia <ref>{{Cite pmid|25041977}}</ref> Adrenomedullin: a vasodilator to treat sepsis? #MMPMID25041977 Pugin J Crit Care 2014[]; 18 (3): 152 PMID25041977show ga Adrenomedullin is a vasodilatory polypeptide with pleiotropic effects secreted by various organs. Adrenomedullin is produced first as a prepropeptide, and then cleaved into mature adrenomedullin and mid-regional proadrenomedullin. Whereas levels of the latter have been shown to correlate with severity of sepsis and carry prognostic value, adrenomedullin plays a role in vascular tone homeostasis. In the previous issue of Critical Care, the infusion of exogenous adrenomedullin is suggested to protect against increased lung endothelial permeability and end-organ dysfunction in a model of pneumococcal pneumonia in mechanically ventilated mice, possibly by stabilizing vascular endothelia. Since adrenomedullin is a strong vasodilatory molecule, further studies are needed to evaluate its potential as a future treatment of sepsis. äAdrenomedullin: a vasodilator to treat sepsis?(epmc).pdf DeepDyve Pubget Overpricing