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10.1681/ASN.2013080899 http://scihub22266oqcxt.onion/10.1681/ASN.2013080899 C4073437!4073437!24525033     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Am+Soc+Nephrol 2014 ; 25 (7): 1599-608 Nephropedia Template TP {{tp|p=24525033|t=2014. Longitudinal Changes of Cardiac Structure and Function in CKD (CASCADE Study) |pdf=|usr=}}{{24525033}} gab.com Text Longitudinal Changes of Cardiac Structure and Function in CKD (CASCADE Study) JO: J Am Soc Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=24525033 #FOAvip Little is known regarding the natural longitudinal changes in cardiac structure and function in CKD. We hypothesized that baseline CKD stage is associated with progressive worsening in cardiac structure and function. We conducted a prospective longitudinal study, recruiting 300 patients with stages 3?5 CKD from a major regional tertiary center and university teaching hospital in Hong Kong. Baseline CKD stages were studied in relation to natural longitudinal changes in echocardiographic and tissue Doppler imaging?derived parameters. Over 1 year, the prevalence of left ventricular (LV) hypertrophy increased from 40.3% to 48.9%, median left atrial volume index increased 4.8 (interquartile range [IQR], 2.1, 7.7) ml/m2 (P<0.001), peak systolic mitral annular velocity decreased 0.5 (IQR, ?1.5, 0.5) cm/s (P<0.001), early diastolic mitral annular velocity decreased 0.5 (IQR, ?1.5, 0.5) cm/s (P<0.001), and eGFR declined 2.0 (IQR, ?5.0, 0.0) ml/min per 1.73 m2. CKD stages 4 and 5 were associated with more baseline abnormalities in cardiac structure and function and predicted greater longitudinal progression in LV mass index (odds ratio [OR], 3.02; 95% confidence interval [95% CI], 1.39 to 6.58), volume index (OR, 2.58; 95% CI, 1.18 to 5.62), and left atrial volume index (OR, 2.61; 95% CI, 1.20 to 5.69) and worse diastolic dysfunction grade (OR, 3.17; 95% CI, 1.16 to 8.69) compared with stage 3a in the fully adjusted analysis. In conclusion, more advanced CKD at baseline may be associated with larger longitudinal increases in LV mass and volume and greater deterioration in diastolic function. Twit Text FOAVip Longitudinal Changes of Cardiac Structure and Function in CKD (CASCADE Study) ????J Am Soc Nephrol http://www.kidney.de/pget.php?&tw=1&pmid=24525033 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24525033 #FOAvip English Wikipedia <ref>{{Cite pmid|24525033}}</ref> Longitudinal Changes of Cardiac Structure and Function in CKD (CASCADE Study) #MMPMID24525033 Cai QZ; Lu XZ; Lu Y; Wang AYM J Am Soc Nephrol 2014[Jul]; 25 (7): 1599-608 PMID24525033show ga Little is known regarding the natural longitudinal changes in cardiac structure and function in CKD. We hypothesized that baseline CKD stage is associated with progressive worsening in cardiac structure and function. We conducted a prospective longitudinal study, recruiting 300 patients with stages 3?5 CKD from a major regional tertiary center and university teaching hospital in Hong Kong. Baseline CKD stages were studied in relation to natural longitudinal changes in echocardiographic and tissue Doppler imaging?derived parameters. Over 1 year, the prevalence of left ventricular (LV) hypertrophy increased from 40.3% to 48.9%, median left atrial volume index increased 4.8 (interquartile range [IQR], 2.1, 7.7) ml/m2 (P<0.001), peak systolic mitral annular velocity decreased 0.5 (IQR, ?1.5, 0.5) cm/s (P<0.001), early diastolic mitral annular velocity decreased 0.5 (IQR, ?1.5, 0.5) cm/s (P<0.001), and eGFR declined 2.0 (IQR, ?5.0, 0.0) ml/min per 1.73 m2. CKD stages 4 and 5 were associated with more baseline abnormalities in cardiac structure and function and predicted greater longitudinal progression in LV mass index (odds ratio [OR], 3.02; 95% confidence interval [95% CI], 1.39 to 6.58), volume index (OR, 2.58; 95% CI, 1.18 to 5.62), and left atrial volume index (OR, 2.61; 95% CI, 1.20 to 5.69) and worse diastolic dysfunction grade (OR, 3.17; 95% CI, 1.16 to 8.69) compared with stage 3a in the fully adjusted analysis. In conclusion, more advanced CKD at baseline may be associated with larger longitudinal increases in LV mass and volume and greater deterioration in diastolic function. äLongitudinal Changes of Cardiac Structure and Function in CKD (CASCADE(epmc).pdf DeepDyve Pubget Overpricing