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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Ann+Gastroenterol
2014 ; 27
(3
): 193-199
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gab.com Text
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Application of confocal laser endomicroscopy in the diagnosis and management of
Barrett s esophagus
#MMPMID24976007
Leggett CL
; Gorospe EC
Ann Gastroenterol
2014[]; 27
(3
): 193-199
PMID24976007
show ga
Confocal laser endomicroscopy is an advanced endoscopic imaging modality that can
be used for the diagnosis of early mucosal dysplasia in various gastrointestinal
conditions. It provides histology-like images at 1000-fold magnification. The
technology offers potential advantages in the diagnosis of Barrett's esophagus
and early esophageal cancer due to the low yield of the current practice of
surveillance endoscopy with biopsies. Confocal laser endomicroscopy has the
potential to eliminate the need for biopsy, establish diagnosis and facilitate
application of endoscopic therapy during the time of actual endoscopy. There are
several studies that have demonstrated reasonable diagnostic accuracy in patients
undergoing surveillance for Barrett's esophagus from tertiary academic medical
centers. However, the application of confocal laser endomicroscopy in routine
clinical endoscopy is still in the process of refinement. Its role in the
diagnosis and treatment of Barrett's-associated dysplasia will continue to evolve
with improvement in technology, criteria for diagnosis and experience among
endoscopists in interpreting confocal imaging.