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10.1186/1471-2105-15-198 http://scihub22266oqcxt.onion/10.1186/1471-2105-15-198 C4071023!4071023 !24938393     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=24938393 &cmd=llinks): Failed to open stream: HTTP request failed! 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CIRCUS: a package for Circos display of structural genome variations from paired-end and mate-pair sequencing data |pdf=|usr=}}{{24938393 }} gab.com Text CIRCUS: a package for Circos display of structural genome variations from paired-end and mate-pair sequencing data JO: BMC Bioinformatics http://www.kidney.de/pget.php?&tw=1&pmid=24938393 #FOAvip BACKGROUND: Detection of large genomic rearrangements, such as large indels, duplications or translocations is now commonly achieved by next generation sequencing (NGS) approaches. Recently, several tools have been developed to analyze NGS data but the resulting files are difficult to interpret without an additional visualization step. Circos (Genome Res, 19:1639-1645, 2009), a Perl script, is a powerful visualization software that requires setting up numerous configuration files with a large number of parameters to handle. R packages like RCircos (BMC Bioinformatics, 14:244, 2013) or ggbio (Genome Biol, 13:R77, 2012) provide functions to display genomic data as circular Circos-like plots. However, these tools are very general and lack the functions needed to filter, format and adjust specific input genomic data. RESULTS: We implemented an R package called CIRCUS to analyze genomic structural variations. It generates both data and configuration files necessary for Circos, to produce graphs. Only few R pre-requisites are necessary. Options are available to deal with heterogeneous data, various chromosome numbers and multi-scale analysis. CONCLUSION: CIRCUS allows fast and versatile analysis of genomic structural variants with Circos plots for users with limited coding skills. Twit Text FOAVip CIRCUS: a package for Circos display of structural genome variations from paired-end and mate-pair sequencing data ????BMC Bioinformatics http://www.kidney.de/pget.php?&tw=1&pmid=24938393 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24938393 #FOAvip English Wikipedia <ref>{{Cite pmid|24938393 }}</ref> CIRCUS: a package for Circos display of structural genome variations from paired-end and mate-pair sequencing data #MMPMID24938393 Naquin D ; d'Aubenton-Carafa Y ; Thermes C ; Silvain M BMC Bioinformatics 2014[Jun]; 15 (ä): 198 PMID24938393 show ga BACKGROUND: Detection of large genomic rearrangements, such as large indels, duplications or translocations is now commonly achieved by next generation sequencing (NGS) approaches. Recently, several tools have been developed to analyze NGS data but the resulting files are difficult to interpret without an additional visualization step. Circos (Genome Res, 19:1639-1645, 2009), a Perl script, is a powerful visualization software that requires setting up numerous configuration files with a large number of parameters to handle. R packages like RCircos (BMC Bioinformatics, 14:244, 2013) or ggbio (Genome Biol, 13:R77, 2012) provide functions to display genomic data as circular Circos-like plots. However, these tools are very general and lack the functions needed to filter, format and adjust specific input genomic data. RESULTS: We implemented an R package called CIRCUS to analyze genomic structural variations. It generates both data and configuration files necessary for Circos, to produce graphs. Only few R pre-requisites are necessary. Options are available to deal with heterogeneous data, various chromosome numbers and multi-scale analysis. CONCLUSION: CIRCUS allows fast and versatile analysis of genomic structural variants with Circos plots for users with limited coding skills. |*Genome [MESH] |*Software Design [MESH] |Genomics/methods [MESH]CIRCUS: a package for Circos display of structural genome variations f(epmc).pdf DeepDyve Pubget Overpricing