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10.5812/ijhrba.9222 http://scihub22266oqcxt.onion/10.5812/ijhrba.9222 C4070159!4070159!24971285     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+High+Risk+Behav+Addict 2013 ; 2 (3): 100-6 Nephropedia Template TP {{tp|p=24971285|t=2013. The Endocannabinoid System: A Putative Role in Neurodegenerative Diseases |pdf=|usr=}}{{24971285}} gab.com Text The Endocannabinoid System: A Putative Role in Neurodegenerative Diseases JO: Int J High Risk Behav Addict http://www.kidney.de/pget.php?&tw=1&pmid=24971285 #FOAvip Background:: Following the characterization of the chemical structure of D9-tetrahydrocannabinol (THC), the main psychoactive constituent of marijuana, researchers have moved on with scientific valuable explorations. Objectives:: The aim of this review is to highlight the role of endocannabinoid system in neurodegenerative diseases. Materials and Methods:: The article is a critical analysis of the most recent data currently present in scientific literature on the subject; a qualitative synthesis of only the most significant articles has been performed. Results:: In central nervous system, endocannabinoids show a neuromodulatory function, often of retrograde type. This way, they play an important role in synaptic plasticity and in cognitive, motor, sensory and affective processes. In addition, in some acute or chronic pathologies of central nervous system, such as neurodegenerative and neuroinflammatory diseases, endocannabinoids can perform a pro-homeostatic and neuroprotective function, through the activation of CB1 and CB2 receptors. Scientific evidence shows that an hypofunction or a dysregulation of the endocannabinoid system may be responsible for some of the symptoms of diseases such as multiple sclerosis, amyotrophic lateral sclerosis, Huntington?s, Parkinson?s and Alzheimer?s diseases. Conclusions:: The important role played by endocannabinoid system promises interesting developments, in particular to evaluate the effectiveness of new drugs in both psychiatry and neurology. Twit Text FOAVip The Endocannabinoid System: A Putative Role in Neurodegenerative Diseases ????Int J High Risk Behav Addict http://www.kidney.de/pget.php?&tw=1&pmid=24971285 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24971285 #FOAvip English Wikipedia <ref>{{Cite pmid|24971285}}</ref> The Endocannabinoid System: A Putative Role in Neurodegenerative Diseases #MMPMID24971285 Di Iorio G; Lupi M; Sarchione F; Matarazzo I; Santacroce R; Petruccelli F; Martinotti G; Di Giannantonio M Int J High Risk Behav Addict 2013[Dec]; 2 (3): 100-6 PMID24971285show ga Background:: Following the characterization of the chemical structure of D9-tetrahydrocannabinol (THC), the main psychoactive constituent of marijuana, researchers have moved on with scientific valuable explorations. Objectives:: The aim of this review is to highlight the role of endocannabinoid system in neurodegenerative diseases. Materials and Methods:: The article is a critical analysis of the most recent data currently present in scientific literature on the subject; a qualitative synthesis of only the most significant articles has been performed. Results:: In central nervous system, endocannabinoids show a neuromodulatory function, often of retrograde type. This way, they play an important role in synaptic plasticity and in cognitive, motor, sensory and affective processes. In addition, in some acute or chronic pathologies of central nervous system, such as neurodegenerative and neuroinflammatory diseases, endocannabinoids can perform a pro-homeostatic and neuroprotective function, through the activation of CB1 and CB2 receptors. Scientific evidence shows that an hypofunction or a dysregulation of the endocannabinoid system may be responsible for some of the symptoms of diseases such as multiple sclerosis, amyotrophic lateral sclerosis, Huntington?s, Parkinson?s and Alzheimer?s diseases. Conclusions:: The important role played by endocannabinoid system promises interesting developments, in particular to evaluate the effectiveness of new drugs in both psychiatry and neurology. äThe Endocannabinoid System: A Putative Role in Neurodegenerative Disea(epmc).pdf DeepDyve Pubget Overpricing