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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Ann+Dermatol
2014 ; 26
(3
): 385-91
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Two Clinically Unusual Cases of Folliculotropic Mycosis Fungoides: One with and
the Other without Syringotropism
#MMPMID24966641
Bakar O
; Seçkin D
; Demirkesen C
; Baykal C
; Büyükbabani N
Ann Dermatol
2014[Jun]; 26
(3
): 385-91
PMID24966641
show ga
Mycosis fungoides is the most common form of cutaneous T-cell lymphoma, and it
rarely exhibits predilection for hair follicle and eccrine gland infiltration.
Here, we present 2 similar cases that display folliculotropism with varying
amounts of follicular mucinosis, with and without syringotropism. The features
observed in both cases were cystic, comedo-like, acneiform lesions; generalized
involvement with loss of body hair; pruritus; and hidradenitis suppurativa-like
lesions. Hypohidrosis as well as nail and palmoplantar involvement with lichen
planopilaris-like clinical features were unique characteristics of the first
case. Despite the well-known aggressive behavior of follicular mycosis fungoides,
the presented cases had a subtle, slowly progressive, but persistent, clinical
course. Folliculotropic and syringotropic mycosis fungoides are variants of
cutaneous T-cell lymphoma. Clinical presentations might be challenging, and
multiple, deep biopsy specimens containing adnexal structures are required for
this critical diagnosis. Aggressive treatment may not be necessary in cases
having an indolent course, especially in those with syringotropism.