Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\24909639
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 BMC+Bioinformatics
2014 ; 15
(ä): 174
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Scan for Motifs: a webserver for the analysis of post-transcriptional regulatory
elements in the 3 untranslated regions (3 UTRs) of mRNAs
#MMPMID24909639
Biswas A
; Brown CM
BMC Bioinformatics
2014[Jun]; 15
(ä): 174
PMID24909639
show ga
BACKGROUND: Gene expression in vertebrate cells may be controlled
post-transcriptionally through regulatory elements in mRNAs. These are usually
located in the untranslated regions (UTRs) of mRNA sequences, particularly the
3'UTRs. RESULTS: Scan for Motifs (SFM) simplifies the process of identifying a
wide range of regulatory elements on alignments of vertebrate 3'UTRs. SFM
includes identification of both RNA Binding Protein (RBP) sites and targets of
miRNAs. In addition to searching pre-computed alignments, the tool provides users
the flexibility to search their own sequences or alignments. The regulatory
elements may be filtered by expected value cutoffs and are cross-referenced back
to their respective sources and literature. The output is an interactive
graphical representation, highlighting potential regulatory elements and overlaps
between them. The output also provides simple statistics and links to related
resources for complementary analyses. The overall process is intuitive and fast.
As SFM is a free web-application, the user does not need to install any software
or databases. CONCLUSIONS: Visualisation of the binding sites of different
classes of effectors that bind to 3'UTRs will facilitate the study of regulatory
elements in 3' UTRs.