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10.1074/jbc.M114.576827

http://scihub22266oqcxt.onion/10.1074/jbc.M114.576827
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C4067212!4067212!24808183
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suck abstract from ncbi


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pmid24808183      J+Biol+Chem 2014 ; 289 (25): 17791-801
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  • A Chemical Biology Approach Demonstrates G Protein ?? Subunits Are Sufficient to Mediate Directional Neutrophil Chemotaxis* #MMPMID24808183
  • Surve CR; Lehmann D; Smrcka AV
  • J Biol Chem 2014[Jun]; 289 (25): 17791-801 PMID24808183show ga
  • Background: G protein ?? (G??) subunits are required for chemokine-dependent directional chemotaxis.Results: A chemical activator of G?? signaling activated G?? signaling and induced directional chemotaxis of neutrophils.Conclusion: G?? signaling is sufficient to induce directional chemotaxis of neutrophils.Significance: Demonstrates that G protein-coupled receptor signals other than G?? are not required for directional migration of neutrophils in response to a gradient.
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