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10.1074/jbc.M114.561183

http://scihub22266oqcxt.onion/10.1074/jbc.M114.561183
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C4067172!4067172!24770418
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suck abstract from ncbi


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pmid24770418      J+Biol+Chem 2014 ; 289 (25): 17392-405
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  • Molecular and Cellular Roles of PI31 (PSMF1) Protein in Regulation of Proteasome Function* #MMPMID24770418
  • Li X; Thompson D; Kumar B; DeMartino GN
  • J Biol Chem 2014[Jun]; 289 (25): 17392-405 PMID24770418show ga
  • Background: PI31 is an HbYX-motif protein that inhibits 20 S proteasome activity in vitro.Results: PI31 exerts multiple HbYX-independent effects on proteasome function in vitro, but has no effect on overall proteasome function or content in cells.Conclusion: PI31 is an in vitro proteasome regulator whose physiologic roles remain to be defined.Significance: PI31 regulation of cellular proteasome function may be limited to specific physiologic conditions and/or to selective proteasome pools.
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