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10.1074/jbc.M114.554717 http://scihub22266oqcxt.onion/10.1074/jbc.M114.554717 C4067169!4067169!24798327     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Biol+Chem 2014 ; 289 (25): 17350-64 Nephropedia Template TP {{tp|p=24798327|t=2014. The Splicing Factor FUBP1 Is Required for the Efficient Splicing of Oncogene MDM2 Pre-mRNA* |pdf=|usr=}}{{24798327}} gab.com Text The Splicing Factor FUBP1 Is Required for the Efficient Splicing of Oncogene MDM2 Pre-mRNA* JO: J Biol Chem http://www.kidney.de/pget.php?&tw=1&pmid=24798327 #FOAvip Background:MDM2 is alternatively spliced into shorter isoforms under DNA damage and in several cancers through unknown mechanisms.Results: FUBP1 inactivation decreases splicing efficiency of an MDM2 minigene and causes exon skipping of endogenous MDM2 under normal conditions. Its overexpression attenuates damage-induced skipping of MDM2 exons.Conclusion: FUBP1 positively regulates efficient MDM2 splicing.Significance: This work uncovers an important mechanism regulating splicing efficiency of the oncogene MDM2. Twit Text FOAVip The Splicing Factor FUBP1 Is Required for the Efficient Splicing of Oncogene MDM2 Pre-mRNA* ????J Biol Chem http://www.kidney.de/pget.php?&tw=1&pmid=24798327 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24798327 #FOAvip English Wikipedia <ref>{{Cite pmid|24798327}}</ref> The Splicing Factor FUBP1 Is Required for the Efficient Splicing of Oncogene MDM2 Pre-mRNA* #MMPMID24798327 Jacob AG; Singh RK; Mohammad F; Bebee TW; Chandler DS J Biol Chem 2014[Jun]; 289 (25): 17350-64 PMID24798327show ga Background:MDM2 is alternatively spliced into shorter isoforms under DNA damage and in several cancers through unknown mechanisms.Results: FUBP1 inactivation decreases splicing efficiency of an MDM2 minigene and causes exon skipping of endogenous MDM2 under normal conditions. Its overexpression attenuates damage-induced skipping of MDM2 exons.Conclusion: FUBP1 positively regulates efficient MDM2 splicing.Significance: This work uncovers an important mechanism regulating splicing efficiency of the oncogene MDM2. äThe Splicing Factor FUBP1 Is Required for the Efficient Splicing of On(epmc).pdf DeepDyve Pubget Overpricing