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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Arch+Virol
2013 ; 158
(12
): 2517-21
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gab.com Text
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English Wikipedia
"Megavirales", a proposed new order for eukaryotic nucleocytoplasmic large DNA
viruses
#MMPMID23812617
Colson P
; De Lamballerie X
; Yutin N
; Asgari S
; Bigot Y
; Bideshi DK
; Cheng XW
; Federici BA
; Van Etten JL
; Koonin EV
; La Scola B
; Raoult D
Arch Virol
2013[Dec]; 158
(12
): 2517-21
PMID23812617
show ga
The nucleocytoplasmic large DNA viruses (NCLDVs) comprise a monophyletic group of
viruses that infect animals and diverse unicellular eukaryotes. The NCLDV group
includes the families Poxviridae, Asfarviridae, Iridoviridae, Ascoviridae,
Phycodnaviridae, Mimiviridae and the proposed family "Marseilleviridae". The
family Mimiviridae includes the largest known viruses, with genomes in excess of
one megabase, whereas the genome size in the other NCLDV families varies from 100
to 400 kilobase pairs. Most of the NCLDVs replicate in the cytoplasm of infected
cells, within so-called virus factories. The NCLDVs share a common ancient
origin, as demonstrated by evolutionary reconstructions that trace approximately
50 genes encoding key proteins involved in viral replication and virion formation
to the last common ancestor of all these viruses. Taken together, these
characteristics lead us to propose assigning an official taxonomic rank to the
NCLDVs as the order "Megavirales", in reference to the large size of the virions
and genomes of these viruses.