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10.1002/ijc.28690 http://scihub22266oqcxt.onion/10.1002/ijc.28690 C4065638!4065638!24375318     free     free     free Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Cancer 2014 ; 135 (12): 2741-8 Nephropedia Template TP {{tp|p=24375318|t=2014. Emerging Role of Nanog in Tumorigenesis and Cancer Stem Cells |pdf=|usr=}}{{24375318}} gab.com Text Emerging Role of Nanog in Tumorigenesis and Cancer Stem Cells JO: Int J Cancer http://www.kidney.de/pget.php?&tw=1&pmid=24375318 #FOAvip Nanog is a transcription factor that is well-established as a key regulator of embryonic stem cell (ESC) maintenance. Recent evidence demonstrates that Nanog is dysregulated and intimately involved in promoting tumorigenesis in part through regulation of the cancer stem cell (CSC) population. Elevated Nanog is associated with poorer outcome in numerous epithelial malignancies. Nanog is enriched in CSCs and ablation of Nanog is sufficient to reduce the CSC pool. Nanog has also been implicated to promote chemoresistance and epithelial-mesenchymal transition (EMT). Insight into the Nanog signaling cascade, upstream regulators and downstream effectors, is beginning to emerge but remains to be fully elucidated. This review highlights the current literature on the emerging role of Nanog in tumorigenesis and CSCs. Twit Text FOAVip Emerging Role of Nanog in Tumorigenesis and Cancer Stem Cells ????Int J Cancer http://www.kidney.de/pget.php?&tw=1&pmid=24375318 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24375318 #FOAvip English Wikipedia <ref>{{Cite pmid|24375318}}</ref> Emerging Role of Nanog in Tumorigenesis and Cancer Stem Cells #MMPMID24375318 Santaliz-Ruiz LE; Xie X; Old M; Teknos TN; Pan Q Int J Cancer 2014[Dec]; 135 (12): 2741-8 PMID24375318show ga Nanog is a transcription factor that is well-established as a key regulator of embryonic stem cell (ESC) maintenance. Recent evidence demonstrates that Nanog is dysregulated and intimately involved in promoting tumorigenesis in part through regulation of the cancer stem cell (CSC) population. Elevated Nanog is associated with poorer outcome in numerous epithelial malignancies. Nanog is enriched in CSCs and ablation of Nanog is sufficient to reduce the CSC pool. Nanog has also been implicated to promote chemoresistance and epithelial-mesenchymal transition (EMT). Insight into the Nanog signaling cascade, upstream regulators and downstream effectors, is beginning to emerge but remains to be fully elucidated. This review highlights the current literature on the emerging role of Nanog in tumorigenesis and CSCs. äEmerging Role of Nanog in Tumorigenesis and Cancer Stem Cells (epmc).pdf DeepDyve Pubget Overpricing