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Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Oncoimmunology 2014 ; 3 (ä): ä Nephropedia Template TP
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Rethinking the role of myeloid-derived suppressor cells in adoptive T-cell therapy for cancer #MMPMID25050213
Arina A
Oncoimmunology 2014[]; 3 (ä): ä PMID25050213show ga
The expansion of cancer-induced myeloid cells is thought to be one of the main obstacles to successful immunotherapy. Nevertheless, in murine tumors undergoing immune-mediated destruction by adoptively transferred T cells, we have recently shown that such cells maintain their immunosuppressive properties. Therefore, adoptive T-cell therapy can, under certain conditions, overcome myeloid cell immunosuppression.