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10.4161/onci.28441

http://scihub22266oqcxt.onion/10.4161/onci.28441
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C4063143!4063143!25050211
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suck abstract from ncbi


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pmid25050211      Oncoimmunology 2014 ; 3 (ä): ä
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  • Macrophages in the liver prevent metastasis by efficiently eliminating circulating tumor cells after monoclonal antibody immunotherapy #MMPMID25050211
  • Gül N; Babes L; Kubes P; van Egmond M
  • Oncoimmunology 2014[]; 3 (ä): ä PMID25050211show ga
  • Monoclonal antibodies (mAbs) are increasingly being used to treat cancer. In response to mAb therapy, we have identified macrophages in the liver as major effector cells removing circulating tumor cells via antibody-dependent phagocytosis, an immune cell-mediated process that prevented liver metastasis. This discovery extends our understanding of the mechanisms of mAb therapy, and may help to optimize mAb-based anticancer therapeutics.
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