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10.2147/JBM.S46255 http://scihub22266oqcxt.onion/10.2147/JBM.S46255 C4062561!4062561!24966707     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Blood+Med 2014 ; 5 (ä): 69-86 Nephropedia Template TP {{tp|p=24966707|t=2014. Hemophagocytic lymphohistiocytosis: review of etiologies and management |pdf=|usr=}}{{24966707}} gab.com Text Hemophagocytic lymphohistiocytosis: review of etiologies and management JO: J Blood Med http://www.kidney.de/pget.php?&tw=1&pmid=24966707 #FOAvip Hemophagocytic lymphohistiocytosis (HLH) covers a wide array of related life-threatening conditions featuring ineffective immunity characterized by an uncontrolled hyperinflammatory response. HLH is often triggered by infection. Familial forms result from genetic defects in natural killer cells and cytotoxic T-cells, typically affecting perforin and intracellular vesicles. HLH is likely under-recognized, which contributes to its high morbidity and mortality. Early recognition is crucial for any reasonable attempt at curative therapy to be made. Current treatment regimens include immunosuppression, immune modulation, chemotherapy, and biological response modification, followed by hematopoietic stem-cell transplant (bone marrow transplant). A number of recent studies have contributed to the understanding of HLH pathophysiology, leading to alternate treatment options; however, much work remains to raise awareness and improve the high morbidity and mortality of these complex conditions. Twit Text FOAVip Hemophagocytic lymphohistiocytosis: review of etiologies and management ????J Blood Med http://www.kidney.de/pget.php?&tw=1&pmid=24966707 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24966707 #FOAvip English Wikipedia <ref>{{Cite pmid|24966707}}</ref> Hemophagocytic lymphohistiocytosis: review of etiologies and management #MMPMID24966707 George MR J Blood Med 2014[]; 5 (ä): 69-86 PMID24966707show ga Hemophagocytic lymphohistiocytosis (HLH) covers a wide array of related life-threatening conditions featuring ineffective immunity characterized by an uncontrolled hyperinflammatory response. HLH is often triggered by infection. Familial forms result from genetic defects in natural killer cells and cytotoxic T-cells, typically affecting perforin and intracellular vesicles. HLH is likely under-recognized, which contributes to its high morbidity and mortality. Early recognition is crucial for any reasonable attempt at curative therapy to be made. Current treatment regimens include immunosuppression, immune modulation, chemotherapy, and biological response modification, followed by hematopoietic stem-cell transplant (bone marrow transplant). A number of recent studies have contributed to the understanding of HLH pathophysiology, leading to alternate treatment options; however, much work remains to raise awareness and improve the high morbidity and mortality of these complex conditions. äHemophagocytic lymphohistiocytosis: review of etiologies and managemen(epmc).pdf DeepDyve Pubget Overpricing