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10.1158/1078-0432.CCR-14-0576

http://scihub22266oqcxt.onion/10.1158/1078-0432.CCR-14-0576
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C4061908!4061908!24803577
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suck abstract from ncbi


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pmid24803577      Clin+Cancer+Res 2014 ; 20 (11): 2817-9
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  • The Microenvironment Matters: Estrogen Deficiency Fuels Cancer Bone Metastases #MMPMID24803577
  • Wright LE; Guise TA
  • Clin Cancer Res 2014[Jun]; 20 (11): 2817-9 PMID24803577show ga
  • Factors released during osteoclastic bone resorption enhance disseminated breast cancer cell progression by stimulating invasiveness, growth and a bone-resorptive phenotype in cancer cells. Post-menopausal bone loss may accelerate progression of breast cancer growth in bone, explaining the anti-cancer benefit of the bone-specific anti-resorptive agent zoledronic acid in the post-menopausal setting.
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