Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=19576316
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Cardiogenic shock without flow-limiting angiographic coronary artery disease:
(from the Should We Emergently Revascularize Occluded Coronary Arteries for
Cardiogenic Shock Trial and Registry)
#MMPMID19576316
French JK
; Harkness S
; Sleeper L
; Wong SC
; Col J
; Dzavik V
; White HD
; Hochman JS
Am J Cardiol
2009[Jul]; 104
(1
): 24-8
PMID19576316
show ga
Myocardial infarction often develops when thrombosis occurs at lesions that have
not previously been flow limiting. However, the development of cardiogenic shock
complicating acute myocardial infarction in such circumstances has received
little attention. The characteristics of 15 patients with cardiogenic shock who
had no flow-limiting angiographic stenoses were compared with those of 767
patients with > or =1 stenosis who were enrolled in the Should We Emergently
Revascularize Occluded Coronary Arteries for Cardiogenic Shock (SHOCK) trial and
registry. Compared with patients with > or =1 flow-limiting stenosis, patients
with no flow-limiting stenoses were less likely to have pulmonary edema on chest
x-ray (29% vs 62%, p = 0.008) and to be white (53% vs 82%, p = 0.011), and they
had lower median highest creatine kinase levels (702 vs 2,731 U/L, p = 0.018).
For SHOCK trial patients, 1-year survival was 49% for patients with > or =1
flow-limiting stenosis and 71% for those with no flow-limiting stenoses (p =
0.268). In conclusion, patients with cardiogenic shock without flow-limiting
stenosis have different characteristics, and potentially disease mechanisms, and
they do not require revascularization.
free
free
free
