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10.1074/jbc.M114.568311

http://scihub22266oqcxt.onion/10.1074/jbc.M114.568311
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C4059126!4059126!24778190
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suck abstract from ncbi


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pmid24778190      J+Biol+Chem 2014 ; 289 (24): 16835-43
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  • The ?-Helical Region in p24?2 Subunit of p24 Protein Cargo Receptor Is Pivotal for the Recognition and Transport of Glycosylphosphatidylinositol-anchored Proteins* #MMPMID24778190
  • Theiler R; Fujita M; Nagae M; Yamaguchi Y; Maeda Y; Kinoshita T
  • J Biol Chem 2014[Jun]; 289 (24): 16835-43 PMID24778190show ga
  • Background: Glycosylphosphatidylinositol-anchored proteins (GPI-APs) depend on p24 cargo receptors for intracellular trafficking.Results: The luminal ?-helical but not GOLD domain of p24?2 was required for efficient GPI-AP transport.Conclusion: A p24 complex containing p24?2 recognizes GPI-AP cargo using the ?-helical region of p24?2.Significance: The ?-helical regions of p24 proteins are involved in complex formation and cargo recognition.
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