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10.1074/jbc.M114.549717 http://scihub22266oqcxt.onion/10.1074/jbc.M114.549717 C4059122!4059122!24790108     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Biol+Chem 2014 ; 289 (24): 16790-801 Nephropedia Template TP {{tp|p=24790108|t=2014. Mis-regulation of Mammalian Target of Rapamycin (mTOR) Complexes Induced by Albuminuria in Proximal Tubules* |pdf=|usr=}}{{24790108}} gab.com Text Mis-regulation of Mammalian Target of Rapamycin (mTOR) Complexes Induced by Albuminuria in Proximal Tubules* JO: J Biol Chem http://www.kidney.de/pget.php?&tw=1&pmid=24790108 #FOAvip Background: There is a correlation between overload of albumin in the lumen of the PT and progression of renal disease.Results: Physiologic albumin concentrations activate the PI3K/mTORC2/PKB/mTORC1/S6K pathway, whereas pathophysiologic concentrations disrupt this pathway overactivating mTORC1.Conclusion: Albumin overload promotes a mis-regulation of mTOR complexes.Significance: These results help to elucidate the mechanism behind mTORC1 activation during renal disease. Twit Text FOAVip Mis-regulation of Mammalian Target of Rapamycin (mTOR) Complexes Induced by Albuminuria in Proximal Tubules* ????J Biol Chem http://www.kidney.de/pget.php?&tw=1&pmid=24790108 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24790108 #FOAvip English Wikipedia <ref>{{Cite pmid|24790108}}</ref> Mis-regulation of Mammalian Target of Rapamycin (mTOR) Complexes Induced by Albuminuria in Proximal Tubules* #MMPMID24790108 Peruchetti DB; Cheng J; Caruso-Neves C; Guggino WB J Biol Chem 2014[Jun]; 289 (24): 16790-801 PMID24790108show ga Background: There is a correlation between overload of albumin in the lumen of the PT and progression of renal disease.Results: Physiologic albumin concentrations activate the PI3K/mTORC2/PKB/mTORC1/S6K pathway, whereas pathophysiologic concentrations disrupt this pathway overactivating mTORC1.Conclusion: Albumin overload promotes a mis-regulation of mTOR complexes.Significance: These results help to elucidate the mechanism behind mTORC1 activation during renal disease. äMis-regulation of Mammalian Target of Rapamycin (mTOR) Complexes Induc(epmc).pdf DeepDyve Pubget Overpricing