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10.1111/ajt.12553 http://scihub22266oqcxt.onion/10.1111/ajt.12553 C4058786!4058786!24472195     free     free     free Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Am+J+Transplant 2014 ; 14 (2): 404-15 Nephropedia Template TP {{tp|p=24472195|t=2014. Kidneys at Higher Risk of Discard: Expanding the Role of Dual Kidney Transplantation |pdf=|usr=}}{{24472195}} gab.com Text Kidneys at Higher Risk of Discard: Expanding the Role of Dual Kidney Transplantation JO: Am J Transplant http://www.kidney.de/pget.php?&tw=1&pmid=24472195 #FOAvip Half of the recovered expanded criteria donor (ECD) kidneys are discarded in the United States. A new kidney allocation system offers kidneys at higher risk of discard, Kidney Donor Profile Index (KDPI) >85%, to a wider geographic area to promote broader sharing and expedite utilization. Dual kidney transplantation (DKT) based on the KDPI is a potential option to streamline allocation of kidneys which otherwise would have been discarded. To assess the clinical utility of the KDPI in kidneys at higher risk of discard, we analyzed the OPTN/UNOS Registry that included the deceased donor kidneys recovered between 2002 and 2012. The primary outcomes were allograft survival, patient survival and discard rate based on different KDPI categories (<80%, 80?90% and >90%). Kidneys with KDPI >90% were associated with increased odds of discard (OR = 1.99, 95% CI 1.74?2.29) compared to ones with KDPI <80%. DKTs of KDPI >90% were associated with lower overall allograft failure (HR = 0.74, 95% CI 0.62?0.89) and better patient survival (HR = 0.79, 95% CI 0.64?0.98) compared to single ECD kidneys with KDPI >90%. Kidneys at higher risk of discard may be offered in the up-front allocation system as a DKT. Further modeling and simulation studies are required to determine a reasonable KDPI cutoff percentile. Twit Text FOAVip Kidneys at Higher Risk of Discard: Expanding the Role of Dual Kidney Transplantation ????Am J Transplant http://www.kidney.de/pget.php?&tw=1&pmid=24472195 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24472195 #FOAvip English Wikipedia <ref>{{Cite pmid|24472195}}</ref> Kidneys at Higher Risk of Discard: Expanding the Role of Dual Kidney Transplantation #MMPMID24472195 Tanriover B; Mohan S; Cohen DJ; Radhakrishnan J; Nickolas TL; Stone PW; Tsapepas DS; Crew RJ; Dube GK; Sandoval PR; Samstein B; Dogan E; Gaston RS; Tanriover JN; Ratner LE; Hardy MA Am J Transplant 2014[Feb]; 14 (2): 404-15 PMID24472195show ga Half of the recovered expanded criteria donor (ECD) kidneys are discarded in the United States. A new kidney allocation system offers kidneys at higher risk of discard, Kidney Donor Profile Index (KDPI) >85%, to a wider geographic area to promote broader sharing and expedite utilization. Dual kidney transplantation (DKT) based on the KDPI is a potential option to streamline allocation of kidneys which otherwise would have been discarded. To assess the clinical utility of the KDPI in kidneys at higher risk of discard, we analyzed the OPTN/UNOS Registry that included the deceased donor kidneys recovered between 2002 and 2012. The primary outcomes were allograft survival, patient survival and discard rate based on different KDPI categories (<80%, 80?90% and >90%). Kidneys with KDPI >90% were associated with increased odds of discard (OR = 1.99, 95% CI 1.74?2.29) compared to ones with KDPI <80%. DKTs of KDPI >90% were associated with lower overall allograft failure (HR = 0.74, 95% CI 0.62?0.89) and better patient survival (HR = 0.79, 95% CI 0.64?0.98) compared to single ECD kidneys with KDPI >90%. Kidneys at higher risk of discard may be offered in the up-front allocation system as a DKT. Further modeling and simulation studies are required to determine a reasonable KDPI cutoff percentile. äKidneys at Higher Risk of Discard: Expanding the Role of Dual Kidney T(epmc).pdf DeepDyve Pubget Overpricing