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10.1158/1078-0432.CCR-13-0633 http://scihub22266oqcxt.onion/10.1158/1078-0432.CCR-13-0633 C4058417!4058417!24756371     free     free     free       Clin+Cancer+Res 2014 ; 20 (12): 3050-6 Nephropedia Template TP {{tp|p=24756371|t=2014. New Strategies in Ewings Sarcoma: Lost in Translation?|pdf=|usr=}}{{24756371}} gab.com Text New Strategies in Ewings Sarcoma: Lost in Translation JO: Clin Cancer Res http://www.kidney.de/pget.php?&tw=1&pmid=24756371 #FOAvip Ewings Sarcoma is the second most common pediatric malignant bone tumor. Aggressive multimodality therapy has led to an improvement in outcomes, particularly in patients with localized disease. However, therapy-related toxicities are non trivial and the prognosis for patients with relapsed and/or metastatic disease continues to be poor. In this article we outline some of the promising therapies that have the potential to change the Ewings Sarcoma therapeutic paradigm in the not too distant future: insulin growth factor receptor inhibitors, targeting of the fusion protein, epigenetic manipulation, poly-ADP-ribose polymerase inhibitors and immunotherapy. Twit Text FOAVip New Strategies in Ewings Sarcoma: Lost in Translation ????Clin Cancer Res http://www.kidney.de/pget.php?&tw=1&pmid=24756371 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24756371 #FOAvip English Wikipedia <ref>{{Cite pmid|24756371}}</ref> New Strategies in Ewings Sarcoma: Lost in Translation? #MMPMID24756371 Arnaldez FI; Helman LJ Clin Cancer Res 2014[Jun]; 20 (12): 3050-6 PMID24756371show ga Ewings Sarcoma is the second most common pediatric malignant bone tumor. Aggressive multimodality therapy has led to an improvement in outcomes, particularly in patients with localized disease. However, therapy-related toxicities are non trivial and the prognosis for patients with relapsed and/or metastatic disease continues to be poor. In this article we outline some of the promising therapies that have the potential to change the Ewings Sarcoma therapeutic paradigm in the not too distant future: insulin growth factor receptor inhibitors, targeting of the fusion protein, epigenetic manipulation, poly-ADP-ribose polymerase inhibitors and immunotherapy. äNew Strategies in Ewings Sarcoma: Lost in Translation?(epmc).pdf DeepDyve Pubget Overpricing