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2014 ; 2014
(ä): 617565
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Electrophysiological studies in patients with pulmonary hypertension: a
retrospective investigation
#MMPMID24977152
Bandorski D
; Schmitt J
; Kurzlechner C
; Erkapic D
; Hamm CW
; Seeger W
; Ghofrani A
; Höltgen R
; Gall H
Biomed Res Int
2014[]; 2014
(ä): 617565
PMID24977152
show ga
Few studies have investigated patients with pulmonary hypertension and
arrhythmias. Data on electrophysiological studies in these patients are rare. In
a retrospective dual-centre design, we analysed data from patients with
indications for electrophysiological study. Fifty-five patients with pulmonary
hypertension were included (Dana Point Classification: group 1: 14, group 2: 23,
group 3: 4, group 4: 8, group 5: 2, and 4 patients with exercised-induced
pulmonary hypertension). Clinical data, 6-minute walk distance, laboratory
values, and echocardiography were collected/performed. Nonsustained ventricular
tachycardia was the most frequent indication (n = 15) for an electrophysiological
study, followed by atrial flutter (n = 14). In summary 36 ablations were
performed and 25 of them were successful (atrial flutter 12 of 14 and
atrioventricular nodal reentrant tachycardia 4 of 4). Fluoroscopy time was 16 ±
14.4 minutes. Electrophysiological studies in patients with pulmonary
hypertension are feasible and safe. Ablation procedures are as effective in these
patients as in non-PAH patients with atrial flutter and atrioventricular nodal
reentrant tachycardia and should be performed likewise. The prognostic relevance
of ventricular stimulations and inducible ventricular tachycardias in these
patients is still unclear and requires further investigation.