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Posterior reversible encephalopathy syndrome in pediatric hematologic-oncologic
disease: literature review and case presentation
#MMPMID24949044
Arzanian MT
; Shamsian BS
; Karimzadeh P
; Kajiyazdi M
; Malek F
; Hammoud M
Iran J Child Neurol
2014[Spr]; 8
(2
): 1-10
PMID24949044
show ga
Posterior reversible encephalopathy syndrome (PRES) is a cliniconeuroradiological
disease entity, which is represented by characteristic magnetic resonance imaging
(MRI) findings of subcortical/cortical hyperintensity in T2-weighted sequences.
It is more often seen in parietaloccipital lobes, and is accompanied by clinical
neurological changes. PRES is a rare central nervous system (CNS) complication in
patients with childhood hematologic-oncologic disese and shows very different
neurological symptoms between patients, ranging from numbness of extremities to
generalized seizure. In this article, we will review PRES presentation in
hematologic-oncologic patients. Then, we will present our patient, a 7-year-old
boy with Evans syndrome on treatment with cyclosporine, mycophenolate mofetil
(MMF) and prednisone, with seizure episodes and MRI finding in favour of PRES.