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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Afr+Health+Sci
2013 ; 13
(4
): 927-32
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Decompensated cirrhosis-related admissions in a large urban hospital in Uganda:
prevalence, clinical and laboratory features and implications for planning
patient management
#MMPMID24940314
Apica BS
; Ocama P
; Seremba E
; Opio KC
; Kagimu MM
Afr Health Sci
2013[Dec]; 13
(4
): 927-32
PMID24940314
show ga
BACKGROUND: Cirrhosis-related complications are a major cause of morbidity and
mortality in areas where its risk factors are endemic. OBJECTIVE: We determined
the prevalence of decompensated cirrhosis among patients on the gastroenterology
service of Mulago Hospital and described the clinical and laboratory features of
these patients. METHODS: All patients admitted to the unit were assessed and
their diagnosis documented. Patients with cirrhosis had clinical features of
decompensation recorded. History of alcohol consumption was taken and testing for
hepatitis B surface antigen (HBsAg) and hepatitis C antibody (anti-HCV)
performed. RESULTS: Between September 2010 and January 2011, we enrolled 482
patients. The majority (53.7%) were male, overall median age 38 years.
Decompensated cirrhosis was diagnosed in 85 (17.6%) patients. Of the 85 patients,
47 (55.3%) gave a history of alcohol intake, HBsAg was positive in 23 (27.1%) and
anti-HCV in 3 (3.5%). Decompensation was defined by ascites among 81 (95.3%)
patients, variceal bleeding in 31 (36.5%), encephalopathy in 20 (23.5%).
CONCLUSION: Cirrhosis is common in Mulago hospital presenting mainly with ascites
and variceal bleeding. Aside from controlling causes of liver diseases,
especially alcohol and hepatitis B virus infection, in the interim it is
necessary to manage complications in patients who already have cirrhosis.
|Adult
[MESH]
|Aged
[MESH]
|Cross-Sectional Studies
[MESH]
|Esophageal and Gastric Varices/complications/*epidemiology
[MESH]
|Female
[MESH]
|Hospitals, Urban
[MESH]
|Humans
[MESH]
|Liver Cirrhosis/*epidemiology/etiology
[MESH]
|Liver Function Tests
[MESH]
|Male
[MESH]
|Middle Aged
[MESH]
|Patient Admission/*statistics & numerical data
[MESH]