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10.1155/2014/628597 http://scihub22266oqcxt.onion/10.1155/2014/628597 C4055362!4055362!24967389     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Biomed+Res+Int 2014 ; 2014 (ä): ä Nephropedia Template TP {{tp|p=24967389|t=2014. To Look Beyond Vasospasm in Aneurysmal Subarachnoid Haemorrhage |pdf=|usr=}}{{24967389}} gab.com Text To Look Beyond Vasospasm in Aneurysmal Subarachnoid Haemorrhage JO: Biomed Res Int http://www.kidney.de/pget.php?&tw=1&pmid=24967389 #FOAvip Delayed cerebral vasospasm has classically been considered the most important and treatable cause of mortality and morbidity in patients with aneurysmal subarachnoid hemorrhage (aSAH). Secondary ischemia (or delayed ischemic neurological deficit, DIND) has been shown to be the leading determinant of poor clinical outcome in patients with aSAH surviving the early phase and cerebral vasospasm has been attributed to being primarily responsible. Recently, various clinical trials aimed at treating vasospasm have produced disappointing results. DIND seems to have a multifactorial etiology and vasospasm may simply represent one contributing factor and not the major determinant. Increasing evidence shows that a series of early secondary cerebral insults may occur following aneurysm rupture (the so-called early brain injury). This further aggravates the initial insult and actually determines the functional outcome. A better understanding of these mechanisms and their prevention in the very early phase is needed to improve the prognosis. The aim of this review is to summarize the existing literature on this topic and so to illustrate how the presence of cerebral vasospasm may not necessarily be a prerequisite for DIND development. The various factors determining DIND that worsen functional outcome and prognosis are then discussed. Twit Text FOAVip To Look Beyond Vasospasm in Aneurysmal Subarachnoid Haemorrhage ????Biomed Res Int http://www.kidney.de/pget.php?&tw=1&pmid=24967389 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24967389 #FOAvip English Wikipedia <ref>{{Cite pmid|24967389}}</ref> To Look Beyond Vasospasm in Aneurysmal Subarachnoid Haemorrhage #MMPMID24967389 Cossu G; Messerer M; Oddo M; Daniel RT Biomed Res Int 2014[]; 2014 (ä): ä PMID24967389show ga Delayed cerebral vasospasm has classically been considered the most important and treatable cause of mortality and morbidity in patients with aneurysmal subarachnoid hemorrhage (aSAH). Secondary ischemia (or delayed ischemic neurological deficit, DIND) has been shown to be the leading determinant of poor clinical outcome in patients with aSAH surviving the early phase and cerebral vasospasm has been attributed to being primarily responsible. Recently, various clinical trials aimed at treating vasospasm have produced disappointing results. DIND seems to have a multifactorial etiology and vasospasm may simply represent one contributing factor and not the major determinant. Increasing evidence shows that a series of early secondary cerebral insults may occur following aneurysm rupture (the so-called early brain injury). This further aggravates the initial insult and actually determines the functional outcome. A better understanding of these mechanisms and their prevention in the very early phase is needed to improve the prognosis. The aim of this review is to summarize the existing literature on this topic and so to illustrate how the presence of cerebral vasospasm may not necessarily be a prerequisite for DIND development. The various factors determining DIND that worsen functional outcome and prognosis are then discussed. äTo Look Beyond Vasospasm in Aneurysmal Subarachnoid Haemorrhage (epmc).pdf DeepDyve Pubget Overpricing