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10.1111/bph.12624 http://scihub22266oqcxt.onion/10.1111/bph.12624 C4055198!4055198!24641580     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Br+J+Pharmacol 2014 ; 171 (12): 2940-50 Nephropedia Template TP {{tp|p=24641580|t=2014. Something old, something new and something very old: drugs for treating type 2 diabetes |pdf=|usr=}}{{24641580}} gab.com Text Something old, something new and something very old: drugs for treating type 2 diabetes JO: Br J Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=24641580 #FOAvip Diabetes mellitus belongs to the most rapidly increasing diseases worldwide. Approximately 90?95% of these patients suffer from type 2 diabetes mellitus, which is characterized by peripheral insulin resistance and the progressive loss of beta-cell function and mass. Considering the complications of this chronic disease, a reliable anti-diabetic treatment is indispensable. An ideal oral anti-diabetic drug should not only correct glucose homeostasis but also preserve or even augment beta-cell function and mass, ameliorate the subclinical inflammation present under insulin-resistant conditions and prevent the macro- and microvascular consequences of diabetes in order to reduce the mortality. Despite the many anti-diabetic drugs already in use, there is an ongoing research for additional drugs, guided by different concepts of the pathogenesis of type 2 diabetes. This review will briefly summarize current oral anti-diabetic drugs. In addition, emerging strategies for the treatment of diabetes will be described, among them the inhibition of glucagon action and anti-inflammatory drugs. Their suitability as ?ideal anti-diabetic drugs? will be discussed. Twit Text FOAVip Something old, something new and something very old: drugs for treating type 2 diabetes ????Br J Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=24641580 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24641580 #FOAvip English Wikipedia <ref>{{Cite pmid|24641580}}</ref> Something old, something new and something very old: drugs for treating type 2 diabetes #MMPMID24641580 Kaiser D; Oetjen E Br J Pharmacol 2014[Jun]; 171 (12): 2940-50 PMID24641580show ga Diabetes mellitus belongs to the most rapidly increasing diseases worldwide. Approximately 90?95% of these patients suffer from type 2 diabetes mellitus, which is characterized by peripheral insulin resistance and the progressive loss of beta-cell function and mass. Considering the complications of this chronic disease, a reliable anti-diabetic treatment is indispensable. An ideal oral anti-diabetic drug should not only correct glucose homeostasis but also preserve or even augment beta-cell function and mass, ameliorate the subclinical inflammation present under insulin-resistant conditions and prevent the macro- and microvascular consequences of diabetes in order to reduce the mortality. Despite the many anti-diabetic drugs already in use, there is an ongoing research for additional drugs, guided by different concepts of the pathogenesis of type 2 diabetes. This review will briefly summarize current oral anti-diabetic drugs. In addition, emerging strategies for the treatment of diabetes will be described, among them the inhibition of glucagon action and anti-inflammatory drugs. Their suitability as ?ideal anti-diabetic drugs? will be discussed. äSomething old, something new and something very old: drugs for treatin(epmc).pdf DeepDyve Pubget Overpricing