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10.1186/gb-2013-14-8-r84 http://scihub22266oqcxt.onion/10.1186/gb-2013-14-8-r84 C4053815!4053815 !23958307     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=23958307 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\23958307 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Genome+Biol 2013 ; 14 (8 ): R84 Nephropedia Template TP {{tp|p=23958307 |t=2013. PROmiRNA: a new miRNA promoter recognition method uncovers the complex regulation of intronic miRNAs |pdf=|usr=}}{{23958307 }} gab.com Text PROmiRNA: a new miRNA promoter recognition method uncovers the complex regulation of intronic miRNAs JO: Genome Biol http://www.kidney.de/pget.php?&tw=1&pmid=23958307 #FOAvip The regulation of intragenic miRNAs by their own intronic promoters is one of the open problems of miRNA biogenesis. Here, we describe PROmiRNA, a new approach for miRNA promoter annotation based on a semi-supervised statistical model trained on deepCAGE data and sequence features. We validate our results with existing annotation, PolII occupancy data and read coverage from RNA-seq data. Compared to previous methods PROmiRNA increases the detection rate of intronic promoters by 30%, allowing us to perform a large-scale analysis of their genomic features, as well as elucidate their contribution to tissue-specific regulation. PROmiRNA can be downloaded from http://promirna.molgen.mpg.de. Twit Text FOAVip PROmiRNA: a new miRNA promoter recognition method uncovers the complex regulation of intronic miRNAs ????Genome Biol http://www.kidney.de/pget.php?&tw=1&pmid=23958307 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=23958307 #FOAvip English Wikipedia <ref>{{Cite pmid|23958307 }}</ref> PROmiRNA: a new miRNA promoter recognition method uncovers the complex regulation of intronic miRNAs #MMPMID23958307 Marsico A ; Huska MR ; Lasserre J ; Hu H ; Vucicevic D ; Musahl A ; Orom U ; Vingron M Genome Biol 2013[Aug]; 14 (8 ): R84 PMID23958307 show ga The regulation of intragenic miRNAs by their own intronic promoters is one of the open problems of miRNA biogenesis. Here, we describe PROmiRNA, a new approach for miRNA promoter annotation based on a semi-supervised statistical model trained on deepCAGE data and sequence features. We validate our results with existing annotation, PolII occupancy data and read coverage from RNA-seq data. Compared to previous methods PROmiRNA increases the detection rate of intronic promoters by 30%, allowing us to perform a large-scale analysis of their genomic features, as well as elucidate their contribution to tissue-specific regulation. PROmiRNA can be downloaded from http://promirna.molgen.mpg.de. |*Algorithms [MESH] |*Promoter Regions, Genetic [MESH] |Brain Chemistry [MESH] |Brain/growth & development/*metabolism [MESH] |Databases, Genetic [MESH] |Gene Expression Regulation, Developmental [MESH] |Genomics/*methods [MESH] |Humans [MESH] |Introns [MESH] |MicroRNAs/chemistry/*genetics [MESH] |Molecular Sequence Annotation [MESH]PROmiRNA: a new miRNA promoter recognition method uncovers the complex(epmc).pdf DeepDyve Pubget Overpricing