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10.1161/CIRCULATIONAHA.113.006855 http://scihub22266oqcxt.onion/10.1161/CIRCULATIONAHA.113.006855 C4053508!4053508!24799515     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Circulation 2014 ; 129 (23): 2380-7 Nephropedia Template TP {{tp|p=24799515|t=2014. Heart Failure with Recovered Ejection Fraction: Clinical Description, Biomarkers, and Outcomes |pdf=|usr=}}{{24799515}} gab.com Text Heart Failure with Recovered Ejection Fraction: Clinical Description, Biomarkers, and Outcomes JO: Circulation http://www.kidney.de/pget.php?&tw=1&pmid=24799515 #FOAvip Background: We hypothesized that heart failure (HF) patients who recover left ventricular function (HF-Recovered) have a distinct clinical phenotype, biology and prognosis compared to HF with reduced ejection fraction (HF-REF) and HF with preserved ejection fraction (HF-PEF). Methods and Results: The Penn Heart Failure Study (PHFS) is a prospective cohort of 1,821 chronic HF patients recruited from tertiary HF clinics. Participants were divided into three categories based on echocardiograms: HF-REF if EF<50%, HF-PEF if EF consistently ?50%, and HF-Recovered if EF on enrollment to PHFS was ?50% but prior EF<50%. A significant portion of HF-Recovered patients had an abnormal biomarker profile at baseline, including 44% with detectable Troponin I, although in comparison, median levels of BNP, sFlt-1, Troponin I and creatinine were greater in HF-REF and HF-PEF patients. In unadjusted Cox models over a maximum follow-up of 8.9 years, the hazard ratio (HR) for death, transplant or ventricular assist device in HF-REF was 4.1 (95%CI 2.4?6.8; p<0.001) and in HF-PEF was 2.3 (95%CI 1.2?4.5; p=0.013), as compared to HF-Recovered. The unadjusted HR for cardiac hospitalization in HF-REF was 2.0 (95%CI 1.5?2.7; p<0.001) and in HF-PEF was 1.3 (95%CI 0.90?2.0; p=0.15), compared to HF-Recovered. Results were similar in adjusted models. Conclusions: HF-Recovered is associated with a better biomarker profile and event-free survival than HF-REF and HF-PEF. However, these patients still have abnormalities in biomarkers and experience a significant number of HF hospitalizations, suggesting persistent HF risk. Twit Text FOAVip Heart Failure with Recovered Ejection Fraction: Clinical Description, Biomarkers, and Outcomes ????Circulation http://www.kidney.de/pget.php?&tw=1&pmid=24799515 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24799515 #FOAvip English Wikipedia <ref>{{Cite pmid|24799515}}</ref> Heart Failure with Recovered Ejection Fraction: Clinical Description, Biomarkers, and Outcomes #MMPMID24799515 Basuray A; French B; Ky B; Vorovich E; Olt C; Sweitzer NK; Cappola TP; Fang JC Circulation 2014[Jun]; 129 (23): 2380-7 PMID24799515show ga Background: We hypothesized that heart failure (HF) patients who recover left ventricular function (HF-Recovered) have a distinct clinical phenotype, biology and prognosis compared to HF with reduced ejection fraction (HF-REF) and HF with preserved ejection fraction (HF-PEF). Methods and Results: The Penn Heart Failure Study (PHFS) is a prospective cohort of 1,821 chronic HF patients recruited from tertiary HF clinics. Participants were divided into three categories based on echocardiograms: HF-REF if EF<50%, HF-PEF if EF consistently ?50%, and HF-Recovered if EF on enrollment to PHFS was ?50% but prior EF<50%. A significant portion of HF-Recovered patients had an abnormal biomarker profile at baseline, including 44% with detectable Troponin I, although in comparison, median levels of BNP, sFlt-1, Troponin I and creatinine were greater in HF-REF and HF-PEF patients. In unadjusted Cox models over a maximum follow-up of 8.9 years, the hazard ratio (HR) for death, transplant or ventricular assist device in HF-REF was 4.1 (95%CI 2.4?6.8; p<0.001) and in HF-PEF was 2.3 (95%CI 1.2?4.5; p=0.013), as compared to HF-Recovered. The unadjusted HR for cardiac hospitalization in HF-REF was 2.0 (95%CI 1.5?2.7; p<0.001) and in HF-PEF was 1.3 (95%CI 0.90?2.0; p=0.15), compared to HF-Recovered. Results were similar in adjusted models. Conclusions: HF-Recovered is associated with a better biomarker profile and event-free survival than HF-REF and HF-PEF. However, these patients still have abnormalities in biomarkers and experience a significant number of HF hospitalizations, suggesting persistent HF risk. äHeart Failure with Recovered Ejection Fraction: Clinical Description, (epmc).pdf DeepDyve Pubget Overpricing